disodium fumarate (food additive) ** full range

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Citizen Science Infered Impact

This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.

SymptomFrequency Found
Asymptomatic: Live in house with person with probable microbiome dysfunctionWorsen
Autonomic Manifestations: irritable bowel syndromeImproves
Autonomic Manifestations: light-headednessWorsen
Autonomic Manifestations: nauseaImproves
Autonomic: Dizziness or faintingImproves
Autonomic: NauseaImproves
Autonomic: Shortness of breathImproves
Comorbid-Mouth: Dry MouthImproves
Comorbid: FibromyalgiaWorsen
Comorbid: Mold Sensitivity / ExposureWorsen
Comorbid: Small intestinal bacterial overgrowth (SIBO)Improves
Gender: FemaleImproves
Immune Manifestations: Abdominal PainImproves
Immune Manifestations: BloatingImproves
Immune Manifestations: general malaiseImproves
Immune Manifestations: Genitorinary / Nocturia - Urinary issuesImproves
Immune Manifestations: new food sensitivitiesWorsen
Immune: Flu-like symptomsImproves
Immune: Sensitivity to smell/food/medication/chemicalsImproves
Immune: Tender / sore lymph nodesImproves
Joint: TendernessImproves
Neurocognitive: Brain FogImproves
Neurocognitive: Difficulty expressing thoughtsImproves
Neurocognitive: Difficulty paying attention for a long period of timeImproves
Neurocognitive: Difficulty understanding thingsImproves
Neurocognitive: Feeling disorientedImproves
Neurocognitive: Problems remembering thingsImproves
Neurocognitive: Unable to focus vision and/or attentionImproves
Neuroendocrine Manifestations: abnormal appetiteImproves
Neuroendocrine Manifestations: Dry Eye (Sicca or Sjogren Syndrome)Improves
Neuroendocrine Manifestations: intolerance of extremes of heat and coldWorsen
Neuroendocrine Manifestations: marked weight change Improves
Neuroendocrine Manifestations: NeuralgiaWorsen
Neuroendocrine Manifestations: Rapid muscular fatiguabilityImproves
Neuroendocrine Manifestations: recurrent feelings of feverishnessImproves
Neuroendocrine Manifestations: subnormal body temperatureImproves
Neuroendocrine: Chills or shiversImproves
Neuroendocrine: Lost or gained weight without tryingImproves
Neurological-Audio: hypersensitivity to noiseImproves
Neurological-Audio: Tinnitus (ringing in ear)Improves
Neurological-Sleep: InsomniaImproves
Neurological-Sleep: Vivid Dreams/NightmaresImproves
Neurological: Difficulty processing information (Understanding)Worsen
Neurological: DisorientationWorsen
Neurological: emotional overloadWorsen
Neurological: Executive Decision Making (Difficulty making)Worsen
Neurological: High degree of Empathy before onsetImproves
Neurological: Neuropathy Worsen
Official Diagnosis: Chronic Fatigue SyndromeImproves
Official Diagnosis: Irritable Bowel SyndromeWorsen
Official Diagnosis: Ulcerative colitisWorsen
Onset: 2010-2020Improves
Pain: Eye painImproves
Pain: Joint painImproves
Pain: Myofascial painImproves
Post-exertional malaise: Difficulty reading after mild physical or mental activityImproves
Post-exertional malaise: Mentally tired after the slightest effortImproves
Post-exertional malaise: Post-exertional malaiseWorsen
Sleep: Daytime drowsinessImproves
Sleep: Need to nap dailyImproves
Sleep: Problems falling asleepImproves
Sleep: Problems staying asleepImproves

Published Science Infered Impact

This is according to the microbiome shifts reported in studies. Clinical studies may show different results

SymptomFrequency Found
Rheumatoid arthritisWorsen
GoutImproves
AsthmaWorsen
ADHDImproves
ME/CFS with IBSImproves
rheumatoid arthritis (RA) and Spondyloarthritis (SpA)Improves
Type 1 DiabetesImproves
Mood DisordersImproves
Systemic Lupus ErythematosusWorsen
Ankylosing spondylitisImproves
EpilepsyWorsen
PsoriasisWorsen
Ulcerative colitisImproves
Multiple SclerosisImproves
SclerosisImproves
FibromyalgiaImproves
Type 2 DiabetesImproves
AtherosclerosisWorsen
Stress / post-traumatic stress disorderImproves
DepressionImproves
Colorectal CancerWorsen
Non-alcoholic Fatty Liver Disease (nafld) NonalcoholicImproves
ME/CFS without IBSWorsen
Chronic Fatigue SyndromeImproves
AcneImproves
Hashimoto's thyroiditisImproves
Non-Celiac Gluten SensitivityWorsen
Liver CirrhosisImproves
neuropsychiatric disorders (PANDAS, PANS)Improves
Histamine Issues From UbiomeImproves
Inflammatory Bowel DiseaseImproves
Chronic Kidney DiseaseImproves
High Blood PressureImproves
AllergiesImproves
SchizophreniaImproves
Irritable Bowel SyndromeImproves
Functional constipation / chronic idiopathic constipationWorsen
Parkinson's DiseaseImproves
Sjögren syndromeImproves
AutismWorsen
Crohn's DiseaseImproves
ObesityImproves
Brain TraumaImproves
Amyotrophic lateral sclerosis (ALS) Motor NeuronImproves
Alzheimer's diseaseImproves
IgA nephropathy (IgAN)Worsen

Bacteria Impacted

Suggest a missed study:

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

📓 - direct citation | 👪 - Impacts Parent Taxa | 👶 - Impacts Child Taxa | 🧙 - Inferred
Taxonomy Rank Effect Citations
Clostridiaceae family Increases 📓 Source Study
Lachnospiraceae family Increases 📓 Source Study
Ruminococcaceae family Increases 📓 Source Study
Acetanaerobacterium genus Increases 👪 Source Study
Acetatifactor genus Increases 👪 Source Study
Acetitomaculum genus Increases 👪 Source Study
Agathobacter genus Increases 👪 Source Study
Agathobaculum genus Increases 👪 Source Study
Alkaliphilus genus Increases 👪 Source Study
Anaerobacter genus Increases 👪 Source Study
Anaerobium genus Increases 👪 Source Study
Anaerobutyricum genus Increases 👪 Source Study
Anaerocolumna genus Increases 👪 Source Study
Anaerofilum genus Increases 👪 Source Study
Anaeromassilibacillus genus Increases 👪 Source Study
Anaerosporobacter genus Increases 👪 Source Study
Anaerotaenia genus Increases 👪 Source Study
Anaerotignum genus Increases 👪 Source Study
Angelakisella genus Increases 👪 Source Study
Anoxynatronum genus Increases 👪 Source Study
Arthromitus genus Increases 👪 Source Study
Beduini genus Increases 👪 Source Study
Bittarella genus Increases 👪 Source Study
Brassicibacter genus Increases 👪 Source Study
Caldisalinibacter genus Increases 👪 Source Study
Caloramator genus Increases 👪 Source Study
Caminicella genus Increases 👪 Source Study
Candidatus Soleaferrea genus Increases 👪 Source Study
Caproiciproducens genus Increases 👪 Source Study
Catonella genus Increases 👪 Source Study
Cellulosilyticum genus Increases 👪 Source Study
Clostridiisalibacter genus Increases 👪 Source Study
Eisenbergiella genus Increases 👪 Source Study
Ethanoligenens genus Increases 👪 Source Study
Faecalicatena genus Increases 👪 Source Study
Falcatimonas genus Increases 👪 Source Study
Fervidicella genus Increases 👪 Source Study
Flavonifractor genus Increases 👪 Source Study
Fonticella genus Increases 👪 Source Study
Fournierella genus Increases 👪 Source Study
Fusicatenibacter genus Increases 👪 Source Study
Gemmiger genus Increases 👪 Source Study
Geosporobacter genus Increases 👪 Source Study
Gorbachella genus Increases 👪 Source Study
Hathewaya genus Increases 👪 Source Study
Herbinix genus Increases 👪 Source Study
Hespellia genus Increases 👪 Source Study
Hungatella genus Increases 👪 Source Study
Hydrogenoanaerobacterium genus Increases 👪 Source Study
Johnsonella genus Increases 👪 Source Study
Lachnoanaerobaculum genus Increases 👪 Source Study
Lachnobacterium genus Increases 👪 Source Study
Lachnotalea genus Increases 👪 Source Study
Lactonifactor genus Increases 👪 Source Study
Lutispora genus Increases 👪 Source Study
Maledivibacter genus Increases 👪 Source Study
Massilioclostridium genus Increases 👪 Source Study
Merdimonas genus Increases 👪 Source Study
Mobilitalea genus Increases 👪 Source Study
Mordavella genus Increases 👪 Source Study
Moryella genus Increases 👪 Source Study
Murimonas genus Increases 👪 Source Study
Natronincola genus Increases 👪 Source Study
Negativibacillus genus Increases 👪 Source Study
Neglecta genus Increases 👪 Source Study
Oceanirhabdus genus Increases 👪 Source Study
Oribacterium genus Increases 👪 Source Study
Oxobacter genus Increases 👪 Source Study
Papillibacter genus Increases 👪 Source Study
Parasporobacterium genus Increases 👪 Source Study
Phocea genus Increases 👪 Source Study
Pseudoflavonifractor genus Increases 👪 Source Study
Robinsoniella genus Increases 👪 Source Study
Ruthenibacterium genus Increases 👪 Source Study
Sarcina genus Increases 👪 Source Study
Sellimonas genus Increases 👪 Source Study
Shuttleworthia genus Increases 👪 Source Study
Sporobacter genus Increases 👪 Source Study
Sporobacterium genus Increases 👪 Source Study
Sporosalibacterium genus Increases 👪 Source Study
Stomatobaculum genus Increases 👪 Source Study
Syntrophococcus genus Increases 👪 Source Study
Tindallia genus Increases 👪 Source Study
Tyzzerella genus Increases 👪 Source Study
Youngiibacter genus Increases 👪 Source Study
Butyrivibrio genus Increases 📓 Source Study
Clostridium genus Increases 📓 Source Study
Faecalibacterium genus Increases 📓 Source Study
Francisella genus Increases 📓 Source Study
Ruminococcus genus Increases 📓 Source Study
'Philomiragia' bacterium species Increases 👪 Source Study
Acuformis perennis species Increases 👪 Source Study
ATCC 25755 species Increases 👪 Source Study
ATCC 27021 species Increases 👪 Source Study
ATCC 27322 species Increases 👪 Source Study
ATCC 43838 species Increases 👪 Source Study
ATCC 51377 species Increases 👪 Source Study
ATCC 55383 species Increases 👪 Source Study
ATCC BAA-623 species Increases 👪 Source Study
ATCC BAA-624 species Increases 👪 Source Study
ATCC VR-331 species Increases 👪 Source Study
Butyrivibrio crossotus species Increases 👪 Source Study
Butyrivibrio fibrisolvens species Increases 👪 Source Study
Butyrivibrio hungatei species Increases 👪 Source Study
Butyrivibrio proteoclasticus species Increases 👪 Source Study
Butyrivibrio sp. species Increases 👪 Source Study
CCUG 58020 species Increases 👪 Source Study
Clostridium acidisoli species Increases 👪 Source Study
Clostridium aestuarii species Increases 👪 Source Study
Clostridium akagii species Increases 👪 Source Study
Clostridium algidicarnis species Increases 👪 Source Study
Clostridium algifaecis species Increases 👪 Source Study
Clostridium amylolyticum species Increases 👪 Source Study
Clostridium aurantibutyricum species Increases 👪 Source Study
Clostridium bornimense species Increases 👪 Source Study
Clostridium cadaveris species Increases 👪 Source Study
Clostridium cavendishii species Increases 👪 Source Study
Clostridium celatum species Increases 👪 Source Study
Clostridium cellulovorans species Increases 👪 Source Study
Clostridium chartatabidum species Increases 👪 Source Study
Clostridium chauvaei species Increases 👪 Source Study
Clostridium chromiireducens species Increases 👪 Source Study
Clostridium cochlearium species Increases 👪 Source Study
Clostridium colicanis species Increases 👪 Source Study
Clostridium collagenovorans species Increases 👪 Source Study
Clostridium cylindrosporum species Increases 👪 Source Study
Clostridium frigidicarnis species Increases 👪 Source Study
Clostridium frigoris species Increases 👪 Source Study
Clostridium ganghwense species Increases 👪 Source Study
Clostridium gasigenes species Increases 👪 Source Study
Clostridium grantii species Increases 👪 Source Study
Clostridium hydrogeniformans species Increases 👪 Source Study
Clostridium intestinale species Increases 👪 Source Study
Clostridium isatidis species Increases 👪 Source Study
Clostridium kluyveri species Increases 👪 Source Study
Clostridium kogasensis species Increases 👪 Source Study
Clostridium lundense species Increases 👪 Source Study
Clostridium maximum species Increases 👪 Source Study
Clostridium neonatale Bouvet et al. 2014 species Increases 👪 Source Study
Clostridium nigeriense species Increases 👪 Source Study
Clostridium oceanicum species Increases 👪 Source Study
Clostridium oryzae species Increases 👪 Source Study
Clostridium paraputrificum species Increases 👪 Source Study
Clostridium phoceensis species Increases 👪 Source Study
Clostridium polyendosporum species Increases 👪 Source Study
Clostridium putrefaciens species Increases 👪 Source Study
Clostridium quinii species Increases 👪 Source Study
Clostridium saccharobutylicum species Increases 👪 Source Study
Clostridium sartagoforme species Increases 👪 Source Study
Clostridium schirmacherense species Increases 👪 Source Study
Clostridium senegalense species Increases 👪 Source Study
Clostridium septicum species Increases 👪 Source Study
Clostridium sp. species Increases 👪 Source Study
Clostridium sp. 14505 species Increases 👪 Source Study
Clostridium sp. 619 species Increases 👪 Source Study
Clostridium sp. 7_2_43FAA species Increases 👪 Source Study
Clostridium sp. AT32 species Increases 👪 Source Study
Clostridium sp. AT4 species Increases 👪 Source Study
Clostridium sp. AUH-JLC235 species Increases 👪 Source Study
Clostridium sp. AWRP species Increases 👪 Source Study
Clostridium sp. BNL1100 species Increases 👪 Source Study
Clostridium sp. BPY5 species Increases 👪 Source Study
Clostridium sp. BS-5 species Increases 👪 Source Study
Clostridium sp. CL-2 species Increases 👪 Source Study
Clostridium sp. Clone-17 species Increases 👪 Source Study
Clostridium sp. Clone-24 species Increases 👪 Source Study
Clostridium sp. Clone-49 species Increases 👪 Source Study
Clostridium sp. CM-C81 species Increases 👪 Source Study
Clostridium sp. CT4 species Increases 👪 Source Study
Clostridium sp. cTPY-17 species Increases 👪 Source Study
Clostridium sp. Culture Jar-8 species Increases 👪 Source Study
Clostridium sp. Culture-1 species Increases 👪 Source Study
Clostridium sp. EDB2 species Increases 👪 Source Study
Clostridium sp. FCB45 species Increases 👪 Source Study
Clostridium sp. FCB90-3 species Increases 👪 Source Study
Clostridium sp. ID5 species Increases 👪 Source Study
Clostridium sp. JN-1 species Increases 👪 Source Study
Clostridium sp. JN-9 species Increases 👪 Source Study
Clostridium sp. JN500901 species Increases 👪 Source Study
Clostridium sp. JPL_22 species Increases 👪 Source Study
Clostridium sp. L2-50 species Increases 👪 Source Study
Clostridium sp. M62/1 species Increases 👪 Source Study
Clostridium sp. Marseille-P2776 species Increases 👪 Source Study
Clostridium sp. Marseille-P3122 species Increases 👪 Source Study
Clostridium sp. Marseille-P3244 species Increases 👪 Source Study
Clostridium sp. MDA2315 species Increases 👪 Source Study
Clostridium sp. MF28 species Increases 👪 Source Study
Clostridium sp. MLG856-1 species Increases 👪 Source Study
Clostridium sp. MSTE9 species Increases 👪 Source Study
Clostridium sp. NML 04A032 species Increases 👪 Source Study
Clostridium sp. NT-1 species Increases 👪 Source Study
Clostridium sp. P301 species Increases 👪 Source Study
Clostridium sp. Pao32 species Increases 👪 Source Study
Clostridium sp. PPf35E6 species Increases 👪 Source Study
Clostridium sp. R96 species Increases 👪 Source Study
Clostridium sp. SR1 species Increases 👪 Source Study
Clostridium sp. SS2/1 species Increases 👪 Source Study
Clostridium sp. SW003 species Increases 👪 Source Study
Clostridium sp. SY8519 species Increases 👪 Source Study
Clostridium sp. TB5 species Increases 👪 Source Study
Clostridium sp. YIT 12069 species Increases 👪 Source Study
Clostridium taeniosporum species Increases 👪 Source Study
Clostridium tarantellae species Increases 👪 Source Study
Clostridium tertium species Increases 👪 Source Study
Clostridium tetani species Increases 👪 Source Study
Clostridium thermobutyricum species Increases 👪 Source Study
Clostridium thermopalmarium species Increases 👪 Source Study
Clostridium uliginosum species Increases 👪 Source Study
Clostridium ventriculi species Increases 👪 Source Study
Clostridium vincentii species Increases 👪 Source Study
CNCM I-3511 [[Francisella piscicida Ottem et al. 2008]] species Increases 👪 Source Study
DSM 1496 species Increases 👪 Source Study
DSM 23729 species Increases 👪 Source Study
DSM 525 species Increases 👪 Source Study
DSM 757 species Increases 👪 Source Study
DSM 791 species Increases 👪 Source Study
DSM 792 species Increases 👪 Source Study
DSM 92 species Increases 👪 Source Study
environmental samples species Increases 👪 Source Study
Francisella sp. CA97-1460 species Increases 👪 Source Study
Francisella sp. FDC440 species Increases 👪 Source Study
Francisella sp. FSC1006 species Increases 👪 Source Study
Francisella sp. TX077310 species Increases 👪 Source Study
JCM 1402 species Increases 👪 Source Study
JCM 1406 species Increases 👪 Source Study
LMG:14027 species Increases 👪 Source Study
Ruminococcus bicirculans species Increases 👪 Source Study
Ruminococcus callidus species Increases 👪 Source Study
Ruminococcus flavefaciens species Increases 👪 Source Study
Ruminococcus gauvreauii species Increases 👪 Source Study
Ruminococcus sp. species Increases 👪 Source Study
Ruminococcus sp. 14531 species Increases 👪 Source Study
Ruminococcus sp. 5_1_39BFAA species Increases 👪 Source Study
Ruminococcus sp. 653 species Increases 👪 Source Study
Ruminococcus sp. DJF_VR66 species Increases 👪 Source Study
Ruminococcus sp. DJF_VR70k1 species Increases 👪 Source Study
Ruminococcus sp. ID1 species Increases 👪 Source Study
Ruminococcus sp. JC304 species Increases 👪 Source Study
Ruminococcus sp. K-1 species Increases 👪 Source Study
Ruminococcus sp. MC_38 species Increases 👪 Source Study
Ruminococcus sp. NK3A76 species Increases 👪 Source Study
Ruminococcus sp. RLB3 species Increases 👪 Source Study
Ruminococcus sp. SR1/5 species Increases 👪 Source Study
Ruminococcus sp. W22 species Increases 👪 Source Study
Ruminococcus sp. WAL 17306 species Increases 👪 Source Study
Ruminococcus sp. YE281 species Increases 👪 Source Study
Ruminococcus sp. ZS2-15 species Increases 👪 Source Study
VPI 1550 species Increases 👪 Source Study
Brucella tularensis species Increases 📓 Source Study
Ruminococcus albus species Increases 📓 Source Study

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