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Citizen Science Infered Impact

This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.

SymptomFrequency FoundRelative Impact
Age: 30-40Improves-9.84
Age: 50-60Improves-8.65
Asymptomatic: Live in house with person with probable microbiome dysfunctionWorsen9.79
Autonomic Manifestations: irritable bowel syndromeWorsen10.84
Autonomic Manifestations: light-headednessImproves-10.45
Autonomic Manifestations: nauseaImproves-6.9399999999999995
Autonomic Manifestations: palpitationsImproves-3.33
Autonomic Manifestations: Postural orthostatic tachycardia syndrome (POTS)Worsen10.3
Autonomic Manifestations: urinary frequency dysfunctionWorsen10.06
Autonomic: Dizziness or faintingImproves-10.66
Autonomic: Heart rate increase after standingWorsen4.64
Autonomic: NauseaImproves-10.16
Autonomic: Shortness of breathImproves-10.25
Comorbid-Mouth: Dry MouthWorsen11.68
Comorbid: FibromyalgiaWorsen8.33
Comorbid: Methylation issues (MTHFR)Worsen9.38
Comorbid: Mold Sensitivity / ExposureWorsen8.59
Comorbid: Multiple Chemical SensitivityImproves-11.13
Comorbid: Small intestinal bacterial overgrowth (SIBO)Worsen10.8
Gender: FemaleImproves-12.65
Immune Manifestations: Abdominal PainWorsen11.64
Immune Manifestations: BloatingWorsen5.39
Immune Manifestations: DiarrheaWorsen9.58
Immune Manifestations: general malaiseWorsen9.68
Immune Manifestations: Genitorinary / Nocturia - Urinary issuesImproves-8.48
Immune Manifestations: new food sensitivitiesWorsen9.93
Immune Manifestations: recurrent flu-like symptomsWorsen9.72
Immune Manifestations: tender lymph nodesImproves-4.86
Immune: Flu-like symptomsWorsen5.95
Immune: Recurrent Sore throatImproves-10.52
Immune: Sensitivity to smell/food/medication/chemicalsImproves-8.73
Immune: Tender / sore lymph nodesImproves-10.41
Infection: Epstein-Barr virusImproves-9.71
Joint: Sudden and severe episodes of painImproves-9.14
Joint: TendernessWorsen10.06
Neurocognitive: Brain FogWorsen10.41
Neurocognitive: Difficulty expressing thoughtsImproves-11.07
Neurocognitive: Difficulty paying attention for a long period of timeWorsen12.6
Neurocognitive: Difficulty understanding thingsWorsen5.24
Neurocognitive: Feeling disorientedWorsen8.63
Neurocognitive: Problems remembering thingsWorsen12.05
Neurocognitive: Slowness of thoughtWorsen7.84
Neurocognitive: Unable to focus vision and/or attentionWorsen11.84
Neuroendocrine Manifestations: abnormal appetiteWorsen9.79
Neuroendocrine Manifestations: Dry Eye (Sicca or Sjogren Syndrome)Worsen9.79
Neuroendocrine Manifestations: Excessive adrenalineImproves-0.94
Neuroendocrine Manifestations: intolerance of extremes of heat and coldImproves-9.38
Neuroendocrine Manifestations: marked weight change Worsen9.54
Neuroendocrine Manifestations: NeuralgiaImproves-9.97
Neuroendocrine Manifestations: Rapid muscular fatiguabilityImproves-10.99
Neuroendocrine Manifestations: recurrent feelings of feverishnessWorsen9.52
Neuroendocrine Manifestations: subnormal body temperatureWorsen10.41
Neuroendocrine: Chills or shiversImproves-9.35
Neuroendocrine: Feeling like you have a high temperatureWorsen4.45
Neuroendocrine: Lack of appetiteWorsen10.43
Neuroendocrine: Lost or gained weight without tryingImproves-9.37
Neurological-Audio: hypersensitivity to noiseImproves-10.03
Neurological-Audio: Tinnitus (ringing in ear)Worsen11.71
Neurological-Sleep: Inability for deep (delta) sleepWorsen9.99
Neurological-Sleep: InsomniaWorsen8.99
Neurological-Sleep: Vivid Dreams/NightmaresImproves-10.94
Neurological-Vision: photophobia (Light Sensitibity)Improves-9.86
Neurological: Cognitive OverloadWorsen9.78
Neurological: Difficulty processing information (Understanding)Worsen10.13
Neurological: DisorientationWorsen8.57
Neurological: emotional overloadWorsen8.32
Neurological: Executive Decision Making (Difficulty making)Improves-10.02
Neurological: High degree of Empathy before onsetWorsen10.7
Neurological: Myoclonic jerks or seizures Improves-9.73
Neurological: Neuropathy Worsen5.49
Neurological: Seasonal Affective Disorder (SAD)Improves-5.64
Neurological: Short-term memory issuesImproves-4.35
Official Diagnosis: Chronic Fatigue SyndromeWorsen10.89
Official Diagnosis: FibromyalgiaWorsen11.31
Official Diagnosis: Irritable Bowel SyndromeWorsen9.89
Official Diagnosis: Ulcerative colitisImproves-10.65
Onset: 2000-2010Worsen10.57
Onset: 2010-2020Worsen12.52
Onset: GradualWorsen11.3
Other: Sensitivity to vibrationsWorsen9.77
Pain: Aching of the eyes or behind the eyesImproves-10.41
Pain: Eye painImproves-10.39
Pain: Joint painImproves-12.57
Pain: Myofascial painWorsen10.59
Post-exertional malaise: Difficulty reading after mild physical or mental activityWorsen12.18
Post-exertional malaise: GeneralWorsen9.69
Post-exertional malaise: Mentally tired after the slightest effortWorsen10.99
Post-exertional malaise: Muscle fatigue after mild physical activityWorsen9.56
Post-exertional malaise: Post-exertional malaiseWorsen11.43
Post-exertional malaise: Rapid muscular fatigability, Worsen10.95
Sleep: Daytime drowsinessWorsen11.23
Sleep: Need to nap dailyImproves-10.15
Sleep: Problems falling asleepImproves-9.52
Sleep: Problems staying asleepWorsen12.65

Published Science Infered Impact

This is according to the microbiome shifts reported in studies. Clinical studies may show different results

SymptomFrequency FoundRelative Impact
AcneWorsen10.3
ADHDImproves-11.14
Allergic Rhinitis (Hay Fever)Improves-3.52
AllergiesWorsen10.12
Alzheimer's diseaseWorsen10.93
Amyotrophic lateral sclerosis (ALS) Motor NeuronWorsen8.05
Ankylosing spondylitisWorsen10.04
AsthmaImproves-9.6
AtherosclerosisImproves-12
AutismWorsen12.76
Autoimmune DiseaseImproves-3.55
Barrett esophagus cancerImproves-9.48
Brain TraumaWorsen9.66
Celiac DiseaseWorsen9.57
Chronic Fatigue SyndromeWorsen11.95
Chronic Kidney DiseaseWorsen9.13
Colorectal CancerImproves-13.2
Crohn's DiseaseWorsen11.77
cystic fibrosisImproves-8.42
DepressionImproves-10.47
EpilepsyWorsen11.49
FibromyalgiaWorsen10.31
Functional constipation / chronic idiopathic constipationImproves-10.37
Gastro-esophageal reflux disease (Gerd) including Barrett's esophagusWorsen9.36
Generalized anxiety disorderImproves-10.46
GoutImproves-7.99
Graves' diseaseWorsen7.82
Hashimoto's thyroiditisImproves-10.94
High Blood PressureWorsen11.14
Histamine IssuesImproves-11.02
Histamine Issues From UbiomeWorsen9.78
hypercholesterolemia (High Cholesterol)Improves-10.35
IgA nephropathy (IgAN)Worsen11.5
Inflammatory Bowel DiseaseWorsen8.99
Irritable Bowel SyndromeWorsen7.99
Juvenile idiopathic arthritisWorsen5.7
Liver CirrhosisWorsen11.63
ME/CFS with IBSImproves-9.01
ME/CFS without IBSImproves-11.08
Metabolic SyndromeWorsen9.79
Mood DisordersImproves-9.74
Multiple SclerosisImproves-11.65
neuropsychiatric disorders (PANDAS, PANS)Improves-9.75
Non-alcoholic Fatty Liver Disease (nafld) NonalcoholicWorsen10.38
Non-Celiac Gluten SensitivityImproves-2.23
ObesityWorsen8.59
Parkinson's DiseaseImproves-10.61
PsoriasisImproves-11.55
Rheumatoid arthritisWorsen10.99
rheumatoid arthritis (RA) and Spondyloarthritis (SpA)Improves-10.69
SchizophreniaImproves-10.06
SclerosisImproves-8.82
Sjögren syndromeImproves-10.34
Small Intestinal Bacterial Overgrowth (SIBO)Improves-10.46
Stress / post-traumatic stress disorderImproves-11.89
Systemic Lupus ErythematosusImproves-11.04
Type 1 DiabetesImproves-10.86
Type 2 DiabetesWorsen11.04
Ulcerative colitisWorsen11.65

Bacteria Impacted

Suggest a missed study:

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

📓 - direct citation | 👪 - Impacts Parent Taxa | 👶 - Impacts Child Taxa | 🧙 - Inferred
Taxonomy Rank Effect Citations
Bacteroides genus Decreases 📓 Source Study
Clostridium genus Decreases 📓 Source Study
Enterorhabdus genus Decreases 📓 Source Study
Methanobrevibacter genus Decreases 📓 Source Study
Prevotella genus Decreases 📓 Source Study
Bacteroides genus Decreases 📓 Source Study
Enterococcus genus Decreases 📓 Source Study
Pseudomonas genus Decreases 📓 Source Study
Staphylococcus genus Decreases 📓 Source Study
Butyrivibrio genus Increases 📓 Source Study
Eubacterium genus Increases 📓 Source Study
Lactobacillus genus Increases 📓 Source Study
Methanosphaera genus Increases 📓 Source Study
Staphylococcus aureus species Decreases 📓 Source Study
Bacteroides thetaiotaomicron species Decreases 📓 Source Study
Bacteroides thetaiotaomicron species Decreases 📓 Source Study
Staphylococcus aureus species Decreases 📓 Source Study
Staphylococcus aureus species Decreases 📓 Source Study
Bacteroides thetaiotaomicron species Decreases 📓 Source Study
Pseudomonas aeruginosa group species Decreases 📓 Source Study
Staphylococcus aureus species Decreases 📓 Source Study
Blautia sp. Marseille-P2398 species Decreases 📓 Source Study
Enterococcus faecalis species Decreases 📓 Source Study
Bacteroides thetaiotaomicron species Decreases 📓 Source Study

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