nsaid ** full range

Check for interactions on Supp.AI


Amazon Site:


Citizen Science Infered Impact

This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.

SymptomFrequency FoundRelative Impact
Age: 30-40Improves-9.84
Age: 50-60Improves-8.65
Asymptomatic: Live in house with person with probable microbiome dysfunctionWorsen9.64
Autonomic Manifestations: irritable bowel syndromeWorsen11.17
Autonomic Manifestations: light-headednessImproves-10.43
Autonomic Manifestations: nauseaImproves-6.84
Autonomic Manifestations: palpitationsImproves-3.33
Autonomic Manifestations: Postural orthostatic tachycardia syndrome (POTS)Worsen10.3
Autonomic Manifestations: urinary frequency dysfunctionWorsen10.06
Autonomic: Dizziness or faintingImproves-10.02
Autonomic: Heart rate increase after standingWorsen4.64
Autonomic: NauseaImproves-10.17
Autonomic: Shortness of breathImproves-9.01
Comorbid-Mouth: Dry MouthWorsen11.68
Comorbid: FibromyalgiaWorsen8.33
Comorbid: Methylation issues (MTHFR)Worsen9.38
Comorbid: Mold Sensitivity / ExposureWorsen8.59
Comorbid: Multiple Chemical SensitivityImproves-11.13
Comorbid: Small intestinal bacterial overgrowth (SIBO)Worsen10.8
Gender: FemaleImproves-12.65
Immune Manifestations: Abdominal PainWorsen11.94
Immune Manifestations: BloatingWorsen5.39
Immune Manifestations: DiarrheaWorsen9.57
Immune Manifestations: general malaiseWorsen10.49
Immune Manifestations: Genitorinary / Nocturia - Urinary issuesImproves-8.47
Immune Manifestations: new food sensitivitiesWorsen9.93
Immune Manifestations: recurrent flu-like symptomsWorsen9.72
Immune Manifestations: tender lymph nodesImproves-4.86
Immune: Flu-like symptomsWorsen5.96
Immune: Recurrent Sore throatImproves-10.53
Immune: Sensitivity to smell/food/medication/chemicalsImproves-8.73
Immune: Tender / sore lymph nodesImproves-10.41
Infection: Epstein-Barr virusImproves-9.71
Joint: Sudden and severe episodes of painImproves-9.14
Joint: TendernessWorsen10.06
Neurocognitive: Brain FogWorsen10.88
Neurocognitive: Difficulty expressing thoughtsImproves-11.07
Neurocognitive: Difficulty paying attention for a long period of timeWorsen12.89
Neurocognitive: Difficulty understanding thingsWorsen5.14
Neurocognitive: Feeling disorientedWorsen8.63
Neurocognitive: Problems remembering thingsWorsen12.03
Neurocognitive: Slowness of thoughtWorsen7.53
Neurocognitive: Unable to focus vision and/or attentionWorsen11.96
Neuroendocrine Manifestations: abnormal appetiteWorsen9.74
Neuroendocrine Manifestations: Dry Eye (Sicca or Sjogren Syndrome)Worsen9.79
Neuroendocrine Manifestations: Excessive adrenalineImproves-0.94
Neuroendocrine Manifestations: intolerance of extremes of heat and coldImproves-9.4
Neuroendocrine Manifestations: marked weight change Worsen9.52
Neuroendocrine Manifestations: NeuralgiaImproves-9.97
Neuroendocrine Manifestations: Rapid muscular fatiguabilityImproves-10.99
Neuroendocrine Manifestations: recurrent feelings of feverishnessWorsen9.52
Neuroendocrine Manifestations: subnormal body temperatureWorsen11.2
Neuroendocrine: Chills or shiversImproves-9.37
Neuroendocrine: Feeling like you have a high temperatureWorsen4.45
Neuroendocrine: Lack of appetiteWorsen10.43
Neuroendocrine: Lost or gained weight without tryingImproves-9.43
Neurological-Audio: hypersensitivity to noiseWorsen9.76
Neurological-Audio: Tinnitus (ringing in ear)Worsen11.99
Neurological-Sleep: Inability for deep (delta) sleepWorsen9.99
Neurological-Sleep: InsomniaWorsen10.21
Neurological-Sleep: Vivid Dreams/NightmaresImproves-10.94
Neurological-Vision: photophobia (Light Sensitibity)Worsen6.66
Neurological: Cognitive OverloadWorsen9.76
Neurological: Difficulty processing information (Understanding)Worsen10.13
Neurological: DisorientationWorsen8.57
Neurological: emotional overloadWorsen8.32
Neurological: Executive Decision Making (Difficulty making)Worsen9.73
Neurological: High degree of Empathy before onsetWorsen11.07
Neurological: Myoclonic jerks or seizures Improves-9.73
Neurological: Seasonal Affective Disorder (SAD)Improves-5.64
Neurological: Short-term memory issuesImproves-4.35
Official Diagnosis: Chronic Fatigue SyndromeWorsen9.53
Official Diagnosis: FibromyalgiaWorsen11.3
Official Diagnosis: Irritable Bowel SyndromeWorsen9.89
Official Diagnosis: Ulcerative colitisImproves-10.65
Onset: 2000-2010Worsen10.57
Onset: 2010-2020Worsen12.58
Onset: GradualWorsen11.3
Other: Sensitivity to vibrationsWorsen9.77
Pain: Aching of the eyes or behind the eyesImproves-10.41
Pain: Eye painImproves-10.41
Pain: Joint painImproves-12.5
Pain: Myofascial painWorsen10.59
Post-exertional malaise: Difficulty reading after mild physical or mental activityWorsen12.18
Post-exertional malaise: GeneralWorsen9.69
Post-exertional malaise: Mentally tired after the slightest effortWorsen10.97
Post-exertional malaise: Muscle fatigue after mild physical activityWorsen9.52
Post-exertional malaise: Post-exertional malaiseWorsen11.17
Post-exertional malaise: Rapid muscular fatigability, Worsen10.95
Sleep: Daytime drowsinessWorsen11.95
Sleep: Need to nap dailyImproves-10.14
Sleep: Problems falling asleepImproves-9.53
Sleep: Problems staying asleepWorsen12.65

Published Science Infered Impact

This is according to the microbiome shifts reported in studies. Clinical studies may show different results

SymptomFrequency FoundRelative Impact
Allergic Rhinitis (Hay Fever)Improves-3.53
Alzheimer's diseaseWorsen11.23
Amyotrophic lateral sclerosis (ALS) Motor NeuronWorsen7.96
Ankylosing spondylitisWorsen10.59
Autoimmune DiseaseImproves-3.29
Barrett esophagus cancerImproves-9.47
Brain TraumaWorsen9.64
Celiac DiseaseWorsen10.44
Chronic Fatigue SyndromeWorsen11.82
Chronic Kidney DiseaseWorsen9.1
Colorectal CancerImproves-13.12
Crohn's DiseaseWorsen11.61
cystic fibrosisImproves-8
Functional constipation / chronic idiopathic constipationImproves-10.37
Gastro-esophageal reflux disease (Gerd) including Barrett's esophagusWorsen9.37
Generalized anxiety disorderImproves-10.46
Graves' diseaseWorsen7.87
Hashimoto's thyroiditisImproves-10.49
High Blood PressureWorsen10.25
Histamine IssuesImproves-11
Histamine Issues From UbiomeWorsen9.78
hypercholesterolemia (High Cholesterol)Improves-10.34
IgA nephropathy (IgAN)Worsen11.49
Inflammatory Bowel DiseaseWorsen9.19
Irritable Bowel SyndromeImproves-9.64
Juvenile idiopathic arthritisWorsen5.7
Liver CirrhosisWorsen11.62
ME/CFS with IBSImproves-8.99
ME/CFS without IBSImproves-11.07
Metabolic SyndromeWorsen9.79
Mood DisordersImproves-9.74
Multiple SclerosisImproves-11.45
neuropsychiatric disorders (PANDAS, PANS)Improves-9.75
Non-alcoholic Fatty Liver Disease (nafld) NonalcoholicWorsen9.37
Non-Celiac Gluten SensitivityImproves-2.22
Parkinson's DiseaseImproves-11.03
Rheumatoid arthritisWorsen10.97
rheumatoid arthritis (RA) and Spondyloarthritis (SpA)Improves-10.67
Sjögren syndromeImproves-9.29
Small Intestinal Bacterial Overgrowth (SIBO)Improves-10.45
Stress / post-traumatic stress disorderImproves-11.88
Systemic Lupus ErythematosusImproves-11.31
Type 1 DiabetesImproves-9.39
Type 2 DiabetesWorsen11.53
Ulcerative colitisWorsen11.46

Bacteria Impacted

Suggest a missed study:

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

📓 - direct citation | 👪 - Impacts Parent Taxa | 👶 - Impacts Child Taxa | 🧙 - Inferred
Taxonomy Rank Effect Citations
Acidaminococcaceae family Increases 📓 Source Study
Desulfovibrionaceae family Increases 📓 Source Study
Enterococcaceae family Increases 📓 Source Study
Erysipelotrichaceae family Increases 📓 Source Study
Absiella genus Increases 👪 Source Study
Acidaminococcus genus Increases 👪 Source Study
Bulleidia genus Increases 👪 Source Study
Candidatus Stoquefichus genus Increases 👪 Source Study
Catellicoccus genus Increases 👪 Source Study
Catenibacterium genus Increases 👪 Source Study
Catenisphaera genus Increases 👪 Source Study
Coprobacillus genus Increases 👪 Source Study
Desulfobaculum genus Increases 👪 Source Study
Desulfohalovibrio genus Increases 👪 Source Study
Dielma genus Increases 👪 Source Study
Eggerthia genus Increases 👪 Source Study
Erysipelatoclostridium genus Increases 👪 Source Study
Erysipelothrix genus Increases 👪 Source Study
Faecalibaculum genus Increases 👪 Source Study
Faecalicoccus genus Increases 👪 Source Study
Faecalitalea genus Increases 👪 Source Study
Holdemanella genus Increases 👪 Source Study
Ileibacterium genus Increases 👪 Source Study
Kandleria genus Increases 👪 Source Study
Lawsonia genus Increases 👪 Source Study
Massilimicrobiota genus Increases 👪 Source Study
Melisococcus genus Increases 👪 Source Study
Merdibacter genus Increases 👪 Source Study
Pilibacter genus Increases 👪 Source Study
Pseudodesulfovibrio genus Increases 👪 Source Study
Solobacterium genus Increases 👪 Source Study
Succiniclasticum genus Increases 👪 Source Study
Succinispira genus Increases 👪 Source Study
Tetragenococcus genus Increases 👪 Source Study
Traorella genus Increases 👪 Source Study
unclassified Erysipelotrichaceae genus Increases 👪 Source Study
Vagococcus genus Increases 👪 Source Study

This site is a free site for non-commercial use and intended to stay a free site for individuals and practioning individual physicians!

Reverse engineering, data scraping and spidering are strictly prohibited and will be prosecuted under 18 U.S.C. § 1030(e)(6) and other statutes. Licensing with an API is available.

If this site is really helpful and you are loaded with money -- Amazon Gift cards are always appreciated to defer operating costs.;-)