peganum harmala (rue) ** full range
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Citizen Science Infered Impact
This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.
| Symptom | Frequency Found | Relative Impact |
|---|---|---|
| Age: 30-40 | Improves | -9.84 |
| Age: 50-60 | Improves | -8.65 |
| Asymptomatic: Live in house with person with probable microbiome dysfunction | Worsen | 9.8 |
| Autonomic Manifestations: irritable bowel syndrome | Worsen | 10.84 |
| Autonomic Manifestations: light-headedness | Improves | -10.45 |
| Autonomic Manifestations: nausea | Improves | -6.9 |
| Autonomic Manifestations: palpitations | Improves | -3.33 |
| Autonomic Manifestations: Postural orthostatic tachycardia syndrome (POTS) | Worsen | 10.3 |
| Autonomic Manifestations: urinary frequency dysfunction | Worsen | 10.06 |
| Autonomic: Dizziness or fainting | Improves | -10.66 |
| Autonomic: Heart rate increase after standing | Worsen | 4.64 |
| Autonomic: Nausea | Improves | -10.16 |
| Autonomic: Shortness of breath | Improves | -10.25 |
| Comorbid-Mouth: Dry Mouth | Worsen | 11.68 |
| Comorbid: Fibromyalgia | Worsen | 8.33 |
| Comorbid: Methylation issues (MTHFR) | Worsen | 9.38 |
| Comorbid: Mold Sensitivity / Exposure | Worsen | 8.59 |
| Comorbid: Multiple Chemical Sensitivity | Improves | -11.13 |
| Comorbid: Small intestinal bacterial overgrowth (SIBO) | Worsen | 10.8 |
| Gender: Female | Improves | -12.65 |
| Immune Manifestations: Abdominal Pain | Worsen | 11.64 |
| Immune Manifestations: Bloating | Worsen | 5.39 |
| Immune Manifestations: Diarrhea | Worsen | 9.58 |
| Immune Manifestations: general malaise | Worsen | 9.69 |
| Immune Manifestations: Genitorinary / Nocturia - Urinary issues | Improves | -8.47 |
| Immune Manifestations: new food sensitivities | Worsen | 9.93 |
| Immune Manifestations: recurrent flu-like symptoms | Worsen | 9.73 |
| Immune Manifestations: tender lymph nodes | Improves | -4.86 |
| Immune: Flu-like symptoms | Worsen | 5.96 |
| Immune: Recurrent Sore throat | Improves | -10.53 |
| Immune: Sensitivity to smell/food/medication/chemicals | Improves | -8.73 |
| Immune: Tender / sore lymph nodes | Improves | -10.41 |
| Infection: Epstein-Barr virus | Improves | -9.71 |
| Joint: Sudden and severe episodes of pain | Improves | -9.14 |
| Joint: Tenderness | Worsen | 10.06 |
| Neurocognitive: Brain Fog | Worsen | 10.41 |
| Neurocognitive: Difficulty expressing thoughts | Improves | -11.07 |
| Neurocognitive: Difficulty paying attention for a long period of time | Worsen | 12.6 |
| Neurocognitive: Difficulty understanding things | Worsen | 5.24 |
| Neurocognitive: Feeling disoriented | Worsen | 8.63 |
| Neurocognitive: Problems remembering things | Worsen | 12.05 |
| Neurocognitive: Slowness of thought | Worsen | 7.86 |
| Neurocognitive: Unable to focus vision and/or attention | Worsen | 11.84 |
| Neuroendocrine Manifestations: abnormal appetite | Worsen | 9.81 |
| Neuroendocrine Manifestations: Dry Eye (Sicca or Sjogren Syndrome) | Worsen | 9.79 |
| Neuroendocrine Manifestations: Excessive adrenaline | Improves | -0.94 |
| Neuroendocrine Manifestations: intolerance of extremes of heat and cold | Improves | -9.38 |
| Neuroendocrine Manifestations: marked weight change | Worsen | 9.54 |
| Neuroendocrine Manifestations: Neuralgia | Improves | -9.97 |
| Neuroendocrine Manifestations: Rapid muscular fatiguability | Improves | -10.99 |
| Neuroendocrine Manifestations: recurrent feelings of feverishness | Worsen | 9.52 |
| Neuroendocrine Manifestations: subnormal body temperature | Worsen | 10.41 |
| Neuroendocrine: Chills or shivers | Improves | -9.35 |
| Neuroendocrine: Feeling like you have a high temperature | Worsen | 4.45 |
| Neuroendocrine: Lack of appetite | Worsen | 10.43 |
| Neuroendocrine: Lost or gained weight without trying | Improves | -9.37 |
| Neurological-Audio: hypersensitivity to noise | Improves | -10.03 |
| Neurological-Audio: Tinnitus (ringing in ear) | Worsen | 11.71 |
| Neurological-Sleep: Inability for deep (delta) sleep | Worsen | 9.99 |
| Neurological-Sleep: Insomnia | Worsen | 8.99 |
| Neurological-Sleep: Vivid Dreams/Nightmares | Improves | -10.94 |
| Neurological-Vision: photophobia (Light Sensitibity) | Improves | -9.87 |
| Neurological: Cognitive Overload | Worsen | 9.78 |
| Neurological: Difficulty processing information (Understanding) | Worsen | 10.13 |
| Neurological: Disorientation | Worsen | 8.57 |
| Neurological: emotional overload | Worsen | 8.32 |
| Neurological: Executive Decision Making (Difficulty making) | Improves | -10.02 |
| Neurological: High degree of Empathy before onset | Worsen | 10.71 |
| Neurological: Myoclonic jerks or seizures | Improves | -9.73 |
| Neurological: Neuropathy | Worsen | 5.48 |
| Neurological: Seasonal Affective Disorder (SAD) | Improves | -5.64 |
| Neurological: Short-term memory issues | Improves | -4.35 |
| Official Diagnosis: Chronic Fatigue Syndrome | Worsen | 10.89 |
| Official Diagnosis: Fibromyalgia | Worsen | 11.3 |
| Official Diagnosis: Irritable Bowel Syndrome | Worsen | 9.89 |
| Official Diagnosis: Ulcerative colitis | Improves | -10.65 |
| Onset: 2000-2010 | Worsen | 10.57 |
| Onset: 2010-2020 | Worsen | 12.52 |
| Onset: Gradual | Worsen | 11.3 |
| Other: Sensitivity to vibrations | Worsen | 9.77 |
| Pain: Aching of the eyes or behind the eyes | Improves | -10.41 |
| Pain: Eye pain | Improves | -10.39 |
| Pain: Joint pain | Improves | -12.57 |
| Pain: Myofascial pain | Worsen | 10.58 |
| Post-exertional malaise: Difficulty reading after mild physical or mental activity | Worsen | 12.18 |
| Post-exertional malaise: General | Worsen | 9.69 |
| Post-exertional malaise: Mentally tired after the slightest effort | Worsen | 10.98 |
| Post-exertional malaise: Muscle fatigue after mild physical activity | Worsen | 9.54 |
| Post-exertional malaise: Post-exertional malaise | Worsen | 11.43 |
| Post-exertional malaise: Rapid muscular fatigability, | Worsen | 10.95 |
| Sleep: Daytime drowsiness | Worsen | 11.24 |
| Sleep: Need to nap daily | Improves | -10.15 |
| Sleep: Problems falling asleep | Improves | -9.52 |
| Sleep: Problems staying asleep | Worsen | 12.65 |
Published Science Infered Impact
This is according to the microbiome shifts reported in studies. Clinical studies may show different results
| Symptom | Frequency Found | Relative Impact |
|---|---|---|
| Acne | Worsen | 10.29 |
| ADHD | Improves | -11.14 |
| Allergic Rhinitis (Hay Fever) | Improves | -3.53 |
| Allergies | Worsen | 10.12 |
| Alzheimer's disease | Worsen | 10.92 |
| Amyotrophic lateral sclerosis (ALS) Motor Neuron | Worsen | 8.01 |
| Ankylosing spondylitis | Worsen | 10 |
| Asthma | Improves | -9.6 |
| Atherosclerosis | Improves | -11.99 |
| Autism | Worsen | 12.51 |
| Autoimmune Disease | Improves | -3.55 |
| Barrett esophagus cancer | Improves | -9.48 |
| Brain Trauma | Worsen | 9.63 |
| Celiac Disease | Worsen | 9.57 |
| Chronic Fatigue Syndrome | Worsen | 11.95 |
| Chronic Kidney Disease | Worsen | 9.11 |
| Colorectal Cancer | Improves | -13.2 |
| Crohn's Disease | Worsen | 11.77 |
| cystic fibrosis | Improves | -8.4 |
| Depression | Improves | -10.47 |
| Epilepsy | Worsen | 11.49 |
| Fibromyalgia | Worsen | 10.29 |
| Functional constipation / chronic idiopathic constipation | Improves | -10.37 |
| Gastro-esophageal reflux disease (Gerd) including Barrett's esophagus | Worsen | 9.36 |
| Generalized anxiety disorder | Improves | -10.46 |
| Gout | Improves | -8.02 |
| Graves' disease | Worsen | 7.86 |
| Hashimoto's thyroiditis | Improves | -10.94 |
| High Blood Pressure | Worsen | 11.14 |
| Histamine Issues | Improves | -11.02 |
| Histamine Issues From Ubiome | Worsen | 9.77 |
| hypercholesterolemia (High Cholesterol) | Improves | -10.35 |
| IgA nephropathy (IgAN) | Worsen | 11.5 |
| Inflammatory Bowel Disease | Worsen | 8.93 |
| Irritable Bowel Syndrome | Worsen | 8.07 |
| Juvenile idiopathic arthritis | Worsen | 5.7 |
| Liver Cirrhosis | Worsen | 11.63 |
| ME/CFS with IBS | Improves | -9.02 |
| ME/CFS without IBS | Improves | -11.08 |
| Metabolic Syndrome | Worsen | 9.79 |
| Mood Disorders | Improves | -9.74 |
| Multiple Sclerosis | Improves | -11.65 |
| neuropsychiatric disorders (PANDAS, PANS) | Improves | -9.75 |
| Non-alcoholic Fatty Liver Disease (nafld) Nonalcoholic | Worsen | 10.37 |
| Non-Celiac Gluten Sensitivity | Improves | -2.23 |
| Obesity | Worsen | 8.53 |
| Parkinson's Disease | Improves | -10.63 |
| Psoriasis | Improves | -11.55 |
| Rheumatoid arthritis | Worsen | 10.99 |
| rheumatoid arthritis (RA) and Spondyloarthritis (SpA) | Improves | -10.69 |
| Schizophrenia | Improves | -10.05 |
| Sclerosis | Improves | -8.82 |
| Sjögren syndrome | Improves | -10.34 |
| Small Intestinal Bacterial Overgrowth (SIBO) | Improves | -10.46 |
| Stress / post-traumatic stress disorder | Improves | -11.89 |
| Systemic Lupus Erythematosus | Improves | -11.03 |
| Type 1 Diabetes | Improves | -10.86 |
| Type 2 Diabetes | Worsen | 11.04 |
| Ulcerative colitis | Worsen | 11.65 |
Bacteria Impacted
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
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