peganum harmala (rue) ** full range
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Citizen Science Infered Impact
This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.
| Symptom | Frequency Found | Relative Impact |
|---|---|---|
| Age: 0-10 | Improves | -9.91 |
| Age: 20-30 | Worsen | 3.9699999999999998 |
| Age: 60-70 | Improves | -9.03 |
| Asymptomatic: No Health Issues | Improves | -2.74 |
| Autonomic Manifestations: irritable bowel syndrome | Improves | -4.82 |
| Autonomic Manifestations: Orthostatic intolerance | Worsen | 9.78 |
| Autonomic: Blurred or tunnel vision after standing | Improves | -9.72 |
| Autonomic: Graying or blacking out after standing | Improves | -9.72 |
| Autonomic: Heart rate increase after standing | Worsen | 9.91 |
| Autonomic: Irregular heartbeats | Worsen | 4.97 |
| Autonomic: Shortness of breath | Improves | -4.89 |
| Blood Type: A Positive | Improves | -10.17 |
| Blood Type: O Positive | Improves | -8.03 |
| Comorbid-Mouth: Bruxism - Jaw cleanching / Teeth grinding | Worsen | 9.83 |
| Comorbid-Mouth: Mouth Sores | Worsen | 2.7 |
| Comorbid-Mouth: TMJ / Dysfunction of the temporomandibular joint syndrome | Worsen | 9.78 |
| Comorbid: Constipation and Explosions (not diarrohea) | Improves | -11.4 |
| Comorbid: High Anxiety | Improves | -8.6 |
| Comorbid: Histamine or Mast Cell issues | Improves | -10.64 |
| Comorbid: Hypothyroidism | Worsen | 10.37 |
| Comorbid: Inflammatory bowel disease | Improves | -10.56 |
| Comorbid: Methylation issues (MTHFR) | Worsen | 2.91 |
| Comorbid: Migraine | Improves | -10.55 |
| Comorbid: Restless Leg | Worsen | 4.45 |
| Comorbid: Small intestinal bacterial overgrowth (SIBO) | Worsen | 10.09 |
| Comorbid: Snoring (NOT Sleep Apnea | Improves | -9.12 |
| DePaul University Fatigue Questionnaire : Fatigue | Improves | -10.12 |
| DePaul University Fatigue Questionnaire : Impaired Memory & concentration | Improves | -11 |
| DePaul University Fatigue Questionnaire : Unrefreshing Sleep, that is waking up feeling tired | Improves | -9.86 |
| Gender: Female | Improves | -9.72 |
| Gender: Male | Improves | -3.65 |
| General: Depression | Worsen | 8.42 |
| General: Headaches | Worsen | 8.33 |
| General: Heavy feeling in arms and legs | Improves | -4.65 |
| General: Myalgia (pain) | Improves | -8.17 |
| Immune Manifestations: Abdominal Pain | Worsen | 9.45 |
| Immune Manifestations: Alcohol Intolerant | Worsen | 7.96 |
| Immune Manifestations: Bloating | Improves | -3.98 |
| Immune Manifestations: Constipation | Worsen | 10 |
| Immune Manifestations: Diarrhea | Worsen | 5.93 |
| Immune Manifestations: general malaise | Worsen | 9.52 |
| Immune Manifestations: Hair loss | Worsen | 8.42 |
| Immune Manifestations: Inflammation (General) | Improves | -7.7 |
| Immune Manifestations: Inflammation of skin, eyes or joints | Improves | -9.13 |
| Immune Manifestations: medication sensitivities. | Improves | -4.93 |
| Immune Manifestations: Mucus in the stool | Worsen | 10.38 |
| Immune Manifestations: tender lymph nodes | Improves | -4.86 |
| Immune: Tender / sore lymph nodes | Improves | -9.72 |
| Infection: Epstein-Barr virus | Improves | -9.71 |
| Infection: Parasite - Other | Improves | -9.9 |
| Joint: Redness | Worsen | 5.58 |
| Joint: Stiffness and swelling | Improves | -9.68 |
| Joint: Tenderness | Worsen | 9.99 |
| Neurocognitive: Absent-mindedness or forgetfulness | Worsen | 9.84 |
| Neurocognitive: Brain Fog | Worsen | 10.07 |
| Neurocognitive: Can only focus on one thing at a time | Improves | -8.51 |
| Neurocognitive: Difficulty paying attention for a long period of time | Worsen | 9.83 |
| Neurocognitive: Problems remembering things | Worsen | 9.53 |
| Neurocognitive: Slowness of thought | Worsen | 8.11 |
| Neurocognitive: Unable to focus vision and/or attention | Worsen | 9.84 |
| Neuroendocrine Manifestations: marked weight change | Worsen | 8.4 |
| Neuroendocrine Manifestations: Muscle weakness | Worsen | 0 |
| Neuroendocrine Manifestations: Neuralgia | Improves | -9.97 |
| Neuroendocrine Manifestations: Paraesthesia (tingling burning of skin) | Improves | -3.61 |
| Neuroendocrine Manifestations: subnormal body temperature | Worsen | 9.83 |
| Neuroendocrine Manifestations: sweating episodes | Worsen | 4.2 |
| Neuroendocrine Manifestations: worsening of symptoms with stress. | Worsen | 3.67 |
| Neuroendocrine: Alcohol intolerance | Worsen | 8.7 |
| Neuroendocrine: Cold limbs (e.g. arms, legs hands) | Worsen | 8.42 |
| Neuroendocrine: Feeling hot or cold for no reason | Worsen | 2.91 |
| Neuroendocrine: Feeling like you have a high temperature | Worsen | 4.45 |
| Neuroendocrine: Feeling like you have a low temperature | Worsen | 9.78 |
| Neuroendocrine: Temperature fluctuations throughout the day | Worsen | 4.39 |
| Neurological-Audio: hypersensitivity to noise | Worsen | 9.84 |
| Neurological-Audio: Tinnitus (ringing in ear) | Worsen | 10.54 |
| Neurological-Sleep: Chaotic diurnal sleep rhythms (Irratic Sleep) | Worsen | 10.01 |
| Neurological-Sleep: Insomnia | Worsen | 3.93 |
| Neurological-Sleep: Night Sweats | Improves | -5.12 |
| Neurological-Sleep: Sleep Apnea | Worsen | 5.55 |
| Neurological-Vision: inability to focus eye/vision | Improves | -7.99 |
| Neurological-Vision: photophobia (Light Sensitibity) | Worsen | 7.03 |
| Neurological: Cognitive Overload | Improves | -4.52 |
| Neurological: Difficulty reading | Worsen | 9.82 |
| Neurological: Dysautonomia | Worsen | 10.6 |
| Neurological: Executive Decision Making (Difficulty making) | Improves | -8.58 |
| Neurological: fasciculations | Worsen | 9.73 |
| Neurological: Impairment of concentration | Improves | -8.49 |
| Neurological: Joint hypermobility | Improves | -10.03 |
| Neurological: Slowed speech | Worsen | 8.34 |
| Neurological: Word-finding problems | Worsen | 8.33 |
| Official Diagnosis: Allergic Rhinitis (Hay Fever) | Improves | -10.24 |
| Official Diagnosis: Autoimmune Disease | Improves | -4.22 |
| Official Diagnosis: Chronic Fatigue Syndrome | Worsen | 8.33 |
| Official Diagnosis: Fibromyalgia | Worsen | 8.32 |
| Official Diagnosis: Irritable Bowel Syndrome | Improves | -8.4 |
| Official Diagnosis: Mast Cell Dysfunction | Improves | -11.05 |
| Onset: 2010-2020 | Worsen | 8.58 |
| Onset: less than 02 years since onset | Worsen | 4.76 |
| Onset: less than 32 years since onset | Improves | -4.54 |
| Other: Sensitivity to mold | Improves | -9.62 |
| Pain: Aching of the eyes or behind the eyes | Improves | -9.72 |
| Pain: Myofascial pain | Improves | -2.04 |
| Post-exertional malaise: Muscle fatigue after mild physical activity | Worsen | 5.67 |
| Post-exertional malaise: Next-day soreness after everyday activities | Improves | -9.56 |
| Post-exertional malaise: Physically tired after minimum exercise | Worsen | 4.51 |
| Post-exertional malaise: Rapid cognitive fatigability, | Worsen | 9.73 |
| Post-exertional malaise: Worsening of symptoms after mild mental activity | Worsen | 9.73 |
| Post-exertional malaise: Worsening of symptoms after mild physical activity | Worsen | 4.67 |
| Sleep: Daytime drowsiness | Worsen | 9.52 |
| Sleep: Problems staying asleep | Worsen | 10.06 |
| Sleep: Waking up early in the morning (e.g. 3 AM) | Worsen | 8.7 |
Published Science Infered Impact
This is according to the microbiome shifts reported in studies. Clinical studies may show different results
| Symptom | Frequency Found | Relative Impact |
|---|---|---|
| Acne | Worsen | 10.3 |
| ADHD | Improves | -11.14 |
| Allergic Rhinitis (Hay Fever) | Improves | -3.56 |
| Allergies | Worsen | 10.11 |
| Alzheimer's disease | Worsen | 10.94 |
| Amyotrophic lateral sclerosis (ALS) Motor Neuron | Worsen | 8.12 |
| Ankylosing spondylitis | Worsen | 9.89 |
| Asthma | Improves | -9.6 |
| Atherosclerosis | Improves | -12 |
| Autism | Worsen | 12.76 |
| Autoimmune Disease | Improves | -3.55 |
| Barrett esophagus cancer | Improves | -9.49 |
| Brain Trauma | Worsen | 9.69 |
| Celiac Disease | Worsen | 9.55 |
| Chronic Fatigue Syndrome | Worsen | 11.96 |
| Chronic Kidney Disease | Worsen | 9.13 |
| Chronic urticaria (Hives) | Improves | -10.08 |
| Colorectal Cancer | Improves | -13.21 |
| Crohn's Disease | Worsen | 11.78 |
| cystic fibrosis | Improves | -8.42 |
| Depression | Improves | -10.46 |
| Epilepsy | Worsen | 11.49 |
| Fibromyalgia | Worsen | 10.32 |
| Functional constipation / chronic idiopathic constipation | Improves | -10.37 |
| Gastro-esophageal reflux disease (Gerd) including Barrett's esophagus | Worsen | 9.35 |
| Generalized anxiety disorder | Improves | -10.48 |
| Gout | Improves | -7.9399999999999995 |
| Graves' disease | Worsen | 7.73 |
| Hashimoto's thyroiditis | Improves | -10.94 |
| High Blood Pressure | Worsen | 11.84 |
| Histamine Issues | Improves | -11.03 |
| Histamine Issues From Ubiome | Worsen | 9.78 |
| hypercholesterolemia (High Cholesterol) | Improves | -10.35 |
| IgA nephropathy (IgAN) | Worsen | 11.5 |
| Inflammatory Bowel Disease | Worsen | 8.84 |
| Irritable Bowel Syndrome | Worsen | 7.62 |
| Juvenile idiopathic arthritis | Worsen | 5.71 |
| Liver Cirrhosis | Worsen | 11.54 |
| ME/CFS with IBS | Improves | -8.99 |
| ME/CFS without IBS | Improves | -11.08 |
| Metabolic Syndrome | Worsen | 9.79 |
| Mood Disorders | Improves | -9.74 |
| Multiple Sclerosis | Improves | -11.65 |
| neuropsychiatric disorders (PANDAS, PANS) | Improves | -9.76 |
| Non-alcoholic Fatty Liver Disease (nafld) Nonalcoholic | Worsen | 10.38 |
| Non-Celiac Gluten Sensitivity | Improves | -2.23 |
| Obesity | Worsen | 10.59 |
| Parkinson's Disease | Improves | -10.6 |
| Psoriasis | Improves | -11.55 |
| Rheumatoid arthritis | Worsen | 10.97 |
| rheumatoid arthritis (RA) and Spondyloarthritis (SpA) | Improves | -10.7 |
| Schizophrenia | Improves | -10.07 |
| Sclerosis | Improves | -8.85 |
| Sjögren syndrome | Improves | -10.34 |
| Small Intestinal Bacterial Overgrowth (SIBO) | Improves | -10.47 |
| Stress / post-traumatic stress disorder | Improves | -11.9 |
| Systemic Lupus Erythematosus | Improves | -11.04 |
| Type 1 Diabetes | Improves | -10.87 |
| Type 2 Diabetes | Worsen | 11.04 |
| Ulcerative colitis | Worsen | 11.65 |
Bacteria Impacted
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
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