}

tolfenamic acid (prescription) ** full range

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Sources

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Correcting for drug impact

Related

Citizen Science Infered Impact

This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.

SymptomFrequency Found
Age: 30-40Worsen
Age: 40-50Worsen
Age: 60-70Worsen
Autonomic Manifestations: irritable bowel syndromeWorsen
Autonomic Manifestations: light-headednessWorsen
Autonomic Manifestations: nauseaWorsen
Autonomic Manifestations: Orthostatic intoleranceImproves
Autonomic Manifestations: Postural orthostatic tachycardia syndrome (POTS)Improves
Autonomic Manifestations: urinary frequency dysfunctionImproves
Autonomic: Blurred or tunnel vision after standingWorsen
Autonomic: Dizziness or faintingImproves
Autonomic: Graying or blacking out after standingWorsen
Autonomic: NauseaImproves
Autonomic: Ocassional Tachycardia (Rapid heart beat)Worsen
Autonomic: Shortness of breathWorsen
Blood Type: O PositiveImproves
Comorbid-Mouth: Bruxism - Jaw cleanching / Teeth grindingImproves
Comorbid-Mouth: Dry MouthImproves
Comorbid-Mouth: Mouth SoresWorsen
Comorbid: High AnxietyImproves
Comorbid: Histamine or Mast Cell issuesImproves
Comorbid: HypothyroidismImproves
Comorbid: Inflammatory bowel disease Worsen
Comorbid: Mold Sensitivity / ExposureImproves
Comorbid: Multiple Chemical SensitivityWorsen
Comorbid: Small intestinal bacterial overgrowth (SIBO)Improves
Comorbid: Snoring (NOT Sleep ApneaWorsen
Gender: FemaleWorsen
General: DepressionImproves
Immune Manifestations: Abdominal PainImproves
Immune Manifestations: Alcohol IntolerantWorsen
Immune Manifestations: BloatingWorsen
Immune Manifestations: ConstipationWorsen
Immune Manifestations: DiarrheaImproves
Immune Manifestations: general malaiseWorsen
Immune Manifestations: Hair lossImproves
Immune Manifestations: Inflammation (General)Worsen
Immune Manifestations: Inflammation of skin, eyes or jointsImproves
Immune Manifestations: Mucus in the stoolWorsen
Immune Manifestations: new food sensitivitiesWorsen
Immune Manifestations: recurrent flu-like symptomsImproves
Immune: Recurrent Sore throatWorsen
Immune: Tender / sore lymph nodesWorsen
Immune: Viral infections with prolonged recovery periodsImproves
Infection: Epstein-Barr virusImproves
Infection: Human Herpesvirus 6 (HHV6)Improves
Infection: MycoplasmaImproves
Infection: Parasite - OtherWorsen
Joint: Stiffness and swellingWorsen
Joint: Sudden and severe episodes of painWorsen
Joint: TendernessImproves
Neurocognitive: Brain FogImproves
Neurocognitive: Difficulty expressing thoughtsWorsen
Neurocognitive: Difficulty paying attention for a long period of timeImproves
Neurocognitive: Difficulty understanding thingsImproves
Neurocognitive: Problems remembering thingsImproves
Neurocognitive: Slowness of thoughtWorsen
Neurocognitive: Unable to focus vision and/or attentionImproves
Neuroendocrine Manifestations: abnormal appetiteImproves
Neuroendocrine Manifestations: Dry Eye (Sicca or Sjogren Syndrome)Worsen
Neuroendocrine Manifestations: intolerance of extremes of heat and coldImproves
Neuroendocrine Manifestations: marked weight change Improves
Neuroendocrine Manifestations: NeuralgiaWorsen
Neuroendocrine Manifestations: Paraesthesia (tingling burning of skin)Worsen
Neuroendocrine Manifestations: Rapid muscular fatiguabilityWorsen
Neuroendocrine Manifestations: recurrent feelings of feverishnessImproves
Neuroendocrine Manifestations: subnormal body temperatureImproves
Neuroendocrine: Alcohol intoleranceWorsen
Neuroendocrine: Feeling like you have a low temperatureImproves
Neuroendocrine: Lack of appetiteImproves
Neuroendocrine: Lost or gained weight without tryingWorsen
Neuroendocrine: Temperature fluctuations throughout the dayWorsen
Neurological-Audio: hypersensitivity to noiseWorsen
Neurological-Audio: Tinnitus (ringing in ear)Improves
Neurological-Sleep: Chaotic diurnal sleep rhythms (Irratic Sleep)Improves
Neurological-Sleep: Inability for deep (delta) sleepImproves
Neurological-Sleep: InsomniaImproves
Neurological-Sleep: Night SweatsWorsen
Neurological-Sleep: Vivid Dreams/NightmaresWorsen
Neurological-Vision: Blurred VisionImproves
Neurological-Vision: inability to focus eye/visionImproves
Neurological-Vision: photophobia (Light Sensitibity)Improves
Neurological: Cognitive OverloadImproves
Neurological: Difficulty processing information (Understanding)Improves
Neurological: DysautonomiaImproves
Neurological: emotional overloadImproves
Neurological: Executive Decision Making (Difficulty making)Worsen
Neurological: fasciculations Improves
Neurological: High degree of Empathy before onsetImproves
Neurological: Joint hypermobilityWorsen
Official Diagnosis: Allergic Rhinitis (Hay Fever)Worsen
Official Diagnosis: Autoimmune DiseaseImproves
Official Diagnosis: Chronic Fatigue SyndromeImproves
Official Diagnosis: FibromyalgiaImproves
Official Diagnosis: Irritable Bowel SyndromeImproves
Official Diagnosis: Mast Cell DysfunctionWorsen
Official Diagnosis: Ulcerative colitisWorsen
Onset: 2010-2020Improves
Onset: GradualImproves
Other: Sensitivity to moldWorsen
Other: Sensitivity to vibrationsImproves
Pain: Aching of the eyes or behind the eyesWorsen
Pain: Eye painWorsen
Pain: Joint painWorsen
Pain: Myofascial painImproves
Pain: Sensitivity to painWorsen
Post-exertional malaise: Difficulty reading after mild physical or mental activityImproves
Post-exertional malaise: GeneralImproves
Post-exertional malaise: Mentally tired after the slightest effortWorsen
Post-exertional malaise: Muscle fatigue after mild physical activityImproves
Post-exertional malaise: Next-day soreness after everyday activitiesImproves
Post-exertional malaise: Physically tired after minimum exerciseWorsen
Post-exertional malaise: Post-exertional malaiseImproves
Post-exertional malaise: Rapid cognitive fatigability, Improves
Post-exertional malaise: Rapid muscular fatigability, Improves
Post-exertional malaise: Worsening of symptoms after mild mental activityImproves
Sleep: Daytime drowsinessWorsen
Sleep: Need to nap dailyWorsen
Sleep: Problems falling asleepWorsen
Sleep: Problems staying asleepImproves
Sleep: Waking up early in the morning (e.g. 3 AM)Improves

Published Science Infered Impact

This is according to the microbiome shifts reported in studies. Clinical studies may show different results

SymptomFrequency Found
Histamine Issues From UbiomeWorsen
Hashimoto's thyroiditisWorsen
Type 2 DiabetesWorsen
ADHDWorsen
Brain TraumaWorsen
Sjögren syndromeImproves
Stress / post-traumatic stress disorderImproves
Small Intestinal Bacterial Overgrowth (SIBO)Improves
AcneWorsen
Generalized anxiety disorderImproves
AsthmaImproves
AtherosclerosisWorsen
Crohn's DiseaseWorsen
Barrett esophagus cancerImproves
Chronic Fatigue SyndromeWorsen
Colorectal CancerImproves
Celiac DiseaseWorsen
Inflammatory Bowel DiseaseImproves
Type 1 DiabetesWorsen
Rheumatoid arthritisWorsen
EpilepsyWorsen
FibromyalgiaWorsen
Functional constipation / chronic idiopathic constipationWorsen
GoutWorsen
Graves' diseaseWorsen
Gastro-esophageal reflux disease (Gerd)Worsen
Non-Celiac Gluten SensitivityImproves
Histamine IssuesImproves
Irritable Bowel SyndromeImproves
IgA nephropathy (IgAN)Worsen
DepressionWorsen
Parkinson's DiseaseImproves
Chronic Kidney DiseaseWorsen
Systemic Lupus ErythematosusImproves
Liver CirrhosisWorsen
Non-alcoholic Fatty Liver Disease Worsen
Metabolic SyndromeWorsen
ME/CFS with IBSWorsen
ME/CFS without IBSImproves
Amyotrophic lateral sclerosis (ALS) Motor NeuronWorsen
neuropsychiatric disorders (PANDAS, PANS)Worsen
High Blood PressureWorsen
PsoriasisImproves
Multiple SclerosisImproves
Mood DisordersWorsen
rheumatoid arthritis (RA) and Spondyloarthritis (SpA)Improves
SchizophreniaImproves
Ankylosing spondylitisImproves
AutismWorsen
Ulcerative colitisWorsen
AllergiesWorsen
SclerosisWorsen
Alzheimer's diseaseWorsen

Bacteria Impacted

}

The following are impacted (to sort click on column title)

Suggest a missed study:
Taxonomy Rank Effect Citations Links
Bacteroidaceae family Decreases Source Study Bacteria also modified by
Bifidobacteriaceae family Decreases Source Study Bacteria also modified by
Bradyrhizobiaceae family Decreases Source Study Bacteria also modified by
Clostridiaceae family Decreases Source Study Bacteria also modified by
Coriobacteriaceae family Decreases Source Study Bacteria also modified by
Desulfovibrionaceae family Decreases Source Study Bacteria also modified by
Enterobacteraceae family Decreases Source Study Bacteria also modified by
Eubacteriaceae family Decreases Source Study Bacteria also modified by
Fusobacteriaceae family Decreases Source Study Bacteria also modified by
Lachnospiraceae family Decreases Source Study Bacteria also modified by
Peptostreptococcaceae family Decreases Source Study Bacteria also modified by
Prevotellaceae family Decreases Source Study Bacteria also modified by
Ruminococcaceae family Decreases Source Study Bacteria also modified by
Streptococcaceae family Decreases Source Study Bacteria also modified by
Verrucomicrobiaceae family Decreases Source Study Bacteria also modified by
Actinomadura genus Decreases Source Study Bacteria also modified by
Akkermansia genus Decreases Source Study Bacteria also modified by
Anaerobacter genus Decreases Source Study Bacteria also modified by
Bilophila genus Decreases Source Study Bacteria also modified by
Clostridioides genus Decreases Source Study Bacteria also modified by
Collinsella genus Decreases Source Study Bacteria also modified by
Coprococcus genus Decreases Source Study Bacteria also modified by
Dorea genus Decreases Source Study Bacteria also modified by
Eggerthella genus Decreases Source Study Bacteria also modified by
Escherichia genus Decreases Source Study Bacteria also modified by
Eubacterium genus Decreases Source Study Bacteria also modified by
Fusibacterium genus Decreases Source Study Bacteria also modified by
Kluyvera genus Decreases Source Study Bacteria also modified by
Paenibacillus genus Decreases Source Study Bacteria also modified by
Peptoclostridium genus Decreases Source Study Bacteria also modified by
Prevotella genus Decreases Source Study Bacteria also modified by
Roseburia genus Decreases Source Study Bacteria also modified by
Ruminococcus genus Decreases Source Study Bacteria also modified by
Streptococcus genus Decreases Source Study Bacteria also modified by
Tissieria genus Decreases Source Study Bacteria also modified by
Veillonella genus Decreases Source Study Bacteria also modified by
Akkermansia muciniphila species Decreases Source Study Bacteria also modified by
Bacteroides vulgatus species Decreases Source Study Bacteria also modified by
Bifidobacterium longum species Decreases Source Study Bacteria also modified by
Bilophila wadsworthia species Decreases Source Study Bacteria also modified by
Clostridioides difficile species Decreases Source Study Bacteria also modified by
Clostridium sp. species Decreases Source Study Bacteria also modified by
Collinsella aerofaciens species Decreases Source Study Bacteria also modified by
Corynebacterium fusiforme species Decreases Source Study Bacteria also modified by
Dorea formicigenerans species Decreases Source Study Bacteria also modified by
Eggerthella lenta species Decreases Source Study Bacteria also modified by
Eubacterium ruminantium species Decreases Source Study Bacteria also modified by
Lactobacillus casei group species Decreases Source Study Bacteria also modified by
Lactobacillus paracasei species Decreases Source Study Bacteria also modified by
Marvinbryantia formatexigens species Decreases Source Study Bacteria also modified by
Roseburia hominis species Decreases Source Study Bacteria also modified by
Roseburia intestinalis species Decreases Source Study Bacteria also modified by
Streptococcus parasanguinis species Decreases Source Study Bacteria also modified by
Streptococcus salivarius species Decreases Source Study Bacteria also modified by
Veillonella parvula species Decreases Source Study Bacteria also modified by

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