Suggestions to counter the impact of methylprednisolone; 6-alpha (prescription)

US These are suggestions that should be reviewed by a medical professional familar with you before implementing. Some suggestions may have adverse reactions with some conditions. The suggestions are built from a logical model using published research on humans and animals. The suggestions may not be applicable to humans.

Click on the substance to see what it modifies. For probiotic sources click here

Items to increase or take

;
Source: Prefered in bulk and organic, with make your own capsules
SubstanceProbability Estimate
inulin (prebiotic) ; 0.585
arabinoxylan oligosaccharides (prebiotic) ; 0.56
resistant starch ; 0.473
resveratrol (grape seed/polyphenols/red wine) ; 0.425
lactulose ; 0.386
ketogenic diet ; 0.382
almonds/ almond skins ; 0.348
red wine ; 0.333
sesame cake/meal ; 0.319
daesiho-tang ; 0.319
Slippery Elm ; 0.309
saccharomyces boulardii (probiotics) ; 0.304

Probiotic Mixtures

See this post on how to add more probiotic mixtures.

As always, probiotics should be reviewed by a knowledgable medical professional before starting.

Positive Impact

These have good impact with NO KNOWN RISK of bad impact. These should be your first choice

  1. Pädia GmbH (DE)/Mambiotic Kapseln : impact 2.6
  2. spain (es) / lactanza hereditum : impact 2.6
  3. enterogermina : impact 1.3

Mixed Impact

You want the highest NET value (Take - Avoid), when there are several with similar values. Take the one with the lowest avoid value.

Ideally you want Take/Avoid to be a 2:1 or higher ratio.

Commercial Probiotic NameNetTakeAvoid
nature's way (au) /restore probiotic bowel & colon health 30s 40.9 87.3 46.4
naturopathica (au) / gastrohealth probiotic dairy free 50 billion 40.5 100.3 59.8
naturopathica (au) / gastrohealth probiotic dairy free 20 bcfu 37.6 77.4 39.8
probiotic pur (de) / realdose nutrition 35.6 82.9 47.3
naturopathica (au) / gastrohealth fibrepro 34.1 48.8 14.7
nature's way (au) / restore probiotic daily health 90s 34.1 54.1 20
nature's way (au) / restore probiotic 30 billion 30s 34.1 54.1 20
blackmore (au) / probiotics+ eczema relief 33 45.8 12.8
theramedix / probiotic 32.8 109.1 76.3
jarrow formulas / bifidus balance® + fos 31.3 65.8 34.5
Realdose 29.7 77 47.3
blackmores (au) / probiotics+ immune defence 27.5 66.7 39.2
blackmores (au) / probiotics + adults daily (90 capsules) 26.8 59.4 32.6
blackmore (au) / probiotics+ daily health 26.8 59.4 32.6
blackmore (au) / probiotics+ bowel support 22.5 64.7 42.2
lifted naturals / mood boosting probiotic 20.9 69.1 48.2
naturopathica (au) / gastrohealth probiotic adults 50+ 17.9 37 19.1
up4 /women's 17.8 58.3 40.5
zint nutrition / probiotic collagen + 17.4 52.4 35
custom probiotics / four strain lactobacilli 16.7 51.7 35
nature's instincts / ultra spore probiotic 16.3 21.1 4.8
spain (es) / ultralevura 15.6 18.5 2.9
spain (es) / axiboulardi 15.6 18.5 2.9
microbiome labs / restorflora 14.5 17.8 3.3
florastor / florastor 13.8 14.5 0.7
optibac / saccharomyces boulardii 13.8 14.5 0.7
organic 3 / yeastbiotic 13.8 14.5 0.7
optibac / for those on antibiotics 13.9 23.8 9.9
naturopathica (au) /gastrohealth probiotic ultimate daily care 100billion 13.9 64.9 51
Jetson / FIT 12.5 27.9 15.4
biospec / probiotic-5 12.3 42.9 30.6
optibac / for every day 12.1 60.3 48.2
optibac / for every day max 10.1 25.3 15.2
vinco / probiotic eight 65 10.1 66.9 56.8
young living/life 9 10.1 70.8 60.7
spain (es) / ns defenbiotic kids 9.7 22.2 12.5
optibac / for your cholesterol 9.5 29.3 19.8
spain (es) / l3.1 9.5 30.6 21.1
optibac / bifidobacteria & fibre 9.5 33.9 24.4
jarrow formula / jarro-dophilus original 9.2 65.3 56.1
custom probiotics / d-lactate free probiotics powder 9 30.1 21.1
quality health(au)/ fridge free probiotic 25b 8.8 20.7 11.9
seed / male version 8.4 71.3 62.9
naturopathica (au)/ gastrohealth probiotic daily care 8.2 22.9 14.7
1 md / complete probiotics platinum 7.7 91.3 83.6
natren / megadophilus 7.5 13.4 5.9
quality health (au) / fridge free* probiotic 60s 7.5 13.4 5.9
bioglan bio (au/ happy probiotic 25 7.5 18.7 11.2
bioglan (au) / healthy kids probiotic choc balls 50s 7.5 18.7 11.2
nature's way (au) / restore probiotic choc balls 60s 7.5 18.7 11.2
solgar / advanced acidophilus plus 7.5 18.7 11.2
bio-k+ 7.3 33.7 26.4
spain (es) / muvagyn probiotico 6.8 16.3 9.5
custom probiotics / six strain probiotic powder 6.8 62.9 56.1
spain (es) / ns florabiotic instant 6.6 21.1 14.5
jarrow formulas / jarro-dophilus mood 6.4 18.9 12.5
visbiome 5.7 57.2 51.5
bayer / trubiotics daily probiotic 5.5 14.1 8.6
trubiotics / one a day 5.5 14.1 8.6
just for tummies / live bacteria 5.3 34.3 29
cytoplan(uk) /dentavital bifidophilus 5.3 40.3 35
Jetson (US) / Mood Probiotics 5 18.9 13.9
spain (es) / vivomixx 5.1 52.6 47.5
up4 / adult 5.1 55.9 50.8
symbiopharm / symbioflo 2 4.9 5.3 0.4
anabolic laboratories / probiotic complete 4.9 16.1 11.2
microbiome labs/ megasporebiotic 4.4 9.9 5.5
powerlabs (au) / ultra blend 4.1 21.3 17.2
bravo europe / freeze-dried bravo 3.9 34.3 30.4
jarrow formulas / jarro-dophilus eps 3.8 54.6 50.8
jarrow formula / ideal bowel support® lp299v® 3.5 23.3 19.8
bioglan bio (au) / happy probiotic 50 3.5 67.5 64
activia drink 3.3 11.9 8.6
nature's way (au) / adult vita gummies daily probiotic 80s 3.1 4.6 1.5
align / align 3.1 4.6 1.5
source naturals / duraflora 3.1 4.6 1.5
thorne / bacillus coagulansvet 60 caps 3.1 4.6 1.5
schiff / digestive advantage 3.1 4.6 1.5
daiichi sankyo healthcare (jp) / panlacmin tablet 3.1 4.6 1.5
ferring / vsl#3 3.1 49.3 46.2
vitamin angels / just thrive 2.4 6.6 4.2
organic 3 / primal soil 2.4 6.6 4.2
reserveage nutrition / beautiflora 2.4 6.6 4.2
enviromedica terraflora sbo probiotic 2.4 6.6 4.2
corebiotic 2.4 6.6 4.2
klaire labs / biospora 2.4 6.6 4.2
perfect pass / perfect pass probiotic bacillus spore 2.4 6.6 4.2
global health trax / threelac 2.4 6.6 4.2
bio-botanical research / proflora4r restorative probiotic 2.4 6.6 4.2
udo's choice /super 8 gold 2.2 76.1 73.9
naturopathica (au) / gastrohealth probiotics 1.8 4 2.2
reg'activ / immune & vitality 1.6 2.9 1.3
naturopathica (au) / gastrohealth women’s probiotic with cranberry 1.6 38.1 36.5
ASEA VIA / BIOME 1.5 86.9 85.4
Nu U (uk) /Bio-Cultures Complex 1.3 35 33.7
genestra brands® hm 0.8 31.2 30.4
spain (es) / profaes4 viajeros 0.8 31.2 30.4
spain (es) / profaes4 edad escolar 0.8 31.2 30.4
amy meyers / primal earth probiotic 0.7 3.3 2.6
microbiome labs /hu58 0.7 3.3 2.6
wakamoto (jp) / strong wakamoto w 0.6 5.9 5.3
solgar / advanced multi-billion dophilus 0.5 34.8 34.3
solgar / advanced 40+ acidophilus 0.5 34.8 34.3
spain (es) / suerobivos 0.2 10.8 10.6
culturelle / culturelle 0.2 10.8 10.6
spain (es) / bivos 0.2 10.8 10.6
spain (es) / kaleidon 0.2 10.8 10.6
digestive care 0.2 10.8 10.6
canada (ca) / calmbiotic 0 8.6 8.6
organic 3 / gutpro 0 61.6 61.6
bravo europe / starter and complex -0.6 54.8 55.4
jarrow formulas / jarro-dophilus® ultra -0.7 75.2 75.9
seed / female version -0.6 79 79.6
organic 3 / primal gut -1.1 100.8 101.9
o'donnell / flora-balance -1.3 1.3 2.6
optibac / for daily immunity -1.3 11.2 12.5
quantum wellness / restora flora -1.4 93.9 95.3
jamieson (can) / probiotic 10 bcfu -2 48.2 50.2
miyarisan (jp) / miyarisan -2.2 3.3 5.5
gnc / ultra probiotic complex -2.5 24.6 27.1
up4 / ultra -2.4 81.4 83.8
spain (es) / alflorex -2.7 2.6 5.3
natren / life start 2 (goat milk-based) -2.7 2.6 5.3
klaire labs / ther-biotic factor 4 -2.7 25.7 28.4
mwsb / candida yeast support -3 10.6 13.6
renew life / ultimate flora -3.1 86 89.1
mutaflor / mutaflor -3.3 2.6 5.9
garden of life / primal defense -3.6 89.5 93.1
Seeking Health / Probiota HistaminX -3.7 49.1 52.8
solaray / mycrobiome probiotic colon formula -3.7 82.3 86
bioglan bio (au) / happy probiotic 100 -3.7 88 91.7
Jetson / Gut Prep -4.1 4 8.1
shin biofermin (jp) /s -4.4 20 24.4
natren / healthy trinity probiotic -4.4 20 24.4
nature's bounty / probioti 10 -4.9 45.3 50.2
bioflorin (deu) / bioflorin -5.5 4 9.5
jarrow formulas / fem dophilus -5.9 19.4 25.3
spain (es) / aquilea intimus -5.9 19.4 25.3
blackmore (au) / probiotics+ womens flora balance -5.9 19.4 25.3
optibac / for women -5.9 19.4 25.3
jarrow formulas / fem-dophilus® -5.9 19.4 25.3
custom probiotics / five strain bifidobacteria -6.6 21.1 27.7
aor / probiotic-3 -6.9 12.5 19.4
naturopathica (au) / gastrohealth antacid -7.2 5.3 12.5
danactive drink -7.2 5.3 12.5
philips / colon health -7.4 20.5 27.9
wakamoto (jp) / wakamoto pharmaceutical intestinal drug -7.4 20.5 27.9
klaire labs / target gb-x -7.5 46 53.5
nature's way (au) / restore probiotic 100 billion -7.4 103 110.4
ecology_allergycare -9.6 39.2 48.8
custom probiotics / b. lactis & b. bifidum probiotic powder -9.9 11.2 21.1
speer labs / emuaid first defense -9.9 24 33.9
renew life men's probiotic - ultimate -10.1 77.7 87.8
elixa / probiotic -10.1 89.8 99.9
douglas laboratories / multi probiotic 40 billion -10.8 83.8 94.6
fürstenmed / lacto-bifido -11.2 74.6 85.8
vita miracle / ultra-30 probiotics -11.3 108.2 119.5
natren / bifido factor -11.9 6.6 18.5
spain (es) / gastrus -12.3 9 21.3
spain (es) / reuteri gotas -12.3 9 21.3
spain (es) / casenbiotic -12.3 9 21.3
spain (es) / gum periobalance -12.3 9 21.3
bioray / cytoflora -12.8 87.1 99.9
hyperbiotics / pro-15 -13 105.6 118.6
Winclove Probiotics / Ecologic®825 -13.4 67.8 81.2
newrhythm / probiotics 20 stains -14.5 106.9 121.4
fairvital / microflora basic -15.4 50.8 66.2
Jetson (US) / Immunity Probiotics -28.6 48.8 77.4

No Known Impact

These appear to have no known direct impact. There is no reason to discontinue them if you are talking them

  1. goodbelly drink
  2. hyperbiotics / pro-dental
  3. natren / digesta-lac
  4. probiotic 3
  5. symbiopharm / symbioflor 1

Flavonoid Foods Suggested

These are a net positive impact -- Odds are that the dominant flavonoids are what is helping. They may be in other foods that have not been studied. Explore!

Flavonoids Suggested

These are a net positive impact -- see what foods they are in (the higher the better!)

Why "Source: Prefered in bulk and organic, with make your own capsules". First, few pre-capsulized supplements are organic, most have fillers and the cost per gram as prepared capsules can be 4x to 50x higher than in bulk. Many folks have reported things did not help until they change to a different brand with different fillers.

Items to decrease or stop

SubstanceProbability Estimate
thiamine hydrochloride (vitamin B1) 1
vitamin b3 (niacin) 1
Cyanocobalamin (Vitamin B-12) 0.986
retinoic acid (Vitamin A derivative) 0.971
Arbutin (polyphenol) 0.971
diosmin (polyphenol) 0.971
folic acid (supplement Vitamin B9) 0.971
Hesperidin (polyphenol) 0.971
pyridoxine hydrochloride (vitamin B6) 0.971
Guaiacol (polyphenol) 0.971
N-Acetyl Cysteine (NAC) 0.971
caffeine (coffee or non-herbal tea) 0.942
vitamin b7 biotin (supplement) (vitamin B7) 0.942
luteolin (flavonoid) 0.913
melatonin supplement 0.884
aspirin (acetylsalicylic acid) 0.768
garlic (allium sativum) 0.333

Contradictory Suggestions

I have seen lactobacillus rhamnosus gg (probiotics) being a TO TAKE and lactobacillus rhamnosus (probiotics) is to avoid. Why? Different studies have different results. Sometimes it is because of other factors (study done on healthy people in one case, on overweight people in the other case). One study may have measured the bacteria you are high in, the other did not. Similarly, one study may have measured the bacteria you are low in, the other did not. There is a forest of qualifications that are nearly impossibly complex to address, and if you try, it will often lack an objective decision that can be demonstrated ("I think...."). Where there are 'conflicts', my usual advice is to just omit it entirely from consideration. If you are taking it, keep taking it. It not, don't.


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