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The information on this site is from academic and research studies. Applicability to humans must be determined by a licensed medical professional.

Suggestions to counter the impact of mianserine hydrochloride (prescription)

US These are suggestions that should be reviewed by a medical professional familar with you before implementing. Some suggestions may have adverse reactions with some conditions. The suggestions are built from a logical model using published research on humans and animals. The suggestions may not be applicable to humans.

Click on the substance to see what it modifies. For probiotic sources click here

Items to increase or take

;
Source: Prefered in bulk and organic, with make your own capsules
SubstanceProbability Estimate
arabinoxylan oligosaccharides (prebiotic) ; 0.551
inulin (prebiotic) ; 0.551
lactulose ; 0.377
ketogenic diet ; 0.333
red wine ; 0.319

Probiotic Mixtures

See this post on how to add more probiotic mixtures.

As always, probiotics should be reviewed by a knowledgable medical professional before starting.

Positive Impact

These have good impact with NO KNOWN RISK of bad impact. These should be your first choice

  1. symbiopharm / symbioflo 2 : impact 5.3
  2. nature's way (au) / adult vita gummies daily probiotic 80s : impact 4
  3. align / align : impact 4
  4. source naturals / duraflora : impact 4
  5. thorne / bacillus coagulansvet 60 caps : impact 4
  6. schiff / digestive advantage : impact 4
  7. daiichi sankyo healthcare (jp) / panlacmin tablet : impact 4
  8. spain (es) / lactanza hereditum : impact 2.6
  9. enterogermina : impact 1.3

Mixed Impact

You want the highest NET value (Take - Avoid), when there are several with similar values. Take the one with the lowest avoid value.

Ideally you want Take/Avoid to be a 2:1 or higher ratio.

Commercial Probiotic NameNetTakeAvoid
nature's way (au) /restore probiotic bowel & colon health 30s 38.3 84.5 46.2
naturopathica (au) / gastrohealth probiotic dairy free 50 billion 37.6 97 59.4
naturopathica (au) / gastrohealth probiotic dairy free 20 bcfu 35 74.6 39.6
naturopathica (au) / gastrohealth fibrepro 32.4 46.9 14.5
nature's way (au) / restore probiotic daily health 90s 32.3 52.1 19.8
nature's way (au) / restore probiotic 30 billion 30s 32.3 52.1 19.8
blackmore (au) / probiotics+ eczema relief 31.1 43.6 12.5
theramedix / probiotic 31 105.6 74.6
jarrow formulas / bifidus balance® + fos 29.1 63.4 34.3
probiotic pur (de) / realdose nutrition 27.1 72.6 45.5
blackmores (au) / probiotics+ immune defence 25.8 64.7 38.9
blackmores (au) / probiotics + adults daily (90 capsules) 25.1 57.4 32.3
blackmore (au) / probiotics+ daily health 25.1 57.4 32.3
Realdose 22.5 68 45.5
lifted naturals / mood boosting probiotic 19.1 67.3 48.2
naturopathica (au) / gastrohealth probiotic adults 50+ 17.2 36.3 19.1
custom probiotics / four strain lactobacilli 16.5 50.2 33.7
up4 /women's 16.5 56.8 40.3
zint nutrition / probiotic collagen + 15.8 50.8 35
blackmore (au) / probiotics+ bowel support 13.8 54.1 40.3
optibac / for those on antibiotics 13.2 23.1 9.9
Jetson / FIT 13.2 27.1 13.9
biospec / probiotic-5 13.2 40.9 27.7
naturopathica (au) /gastrohealth probiotic ultimate daily care 100billion 12.6 63.4 50.8
optibac / for every day 11.2 59.4 48.2
nature's instincts / ultra spore probiotic 9.9 13.2 3.3
optibac / for every day max 9.9 25.1 15.2
custom probiotics / d-lactate free probiotics powder 9.9 29.7 19.8
vinco / probiotic eight 65 9.9 65.3 55.4
young living/life 9 9.9 69.3 59.4
spain (es) / ns defenbiotic kids 9.3 21.8 12.5
optibac / bifidobacteria & fibre 9.3 33.7 24.4
spain (es) / ultralevura 8.6 11.2 2.6
spain (es) / axiboulardi 8.6 11.2 2.6
quality health(au)/ fridge free probiotic 25b 8.6 20.5 11.9
spain (es) / l3.1 8.6 29.7 21.1
1 md / complete probiotics platinum 8.6 89.1 80.5
naturopathica (au)/ gastrohealth probiotic daily care 7.9 22.4 14.5
seed / male version 7.9 67.3 59.4
microbiome labs / restorflora 7.3 10.6 3.3
natren / megadophilus 7.3 13.2 5.9
quality health (au) / fridge free* probiotic 60s 7.3 13.2 5.9
bioglan bio (au/ happy probiotic 25 7.3 18.5 11.2
bioglan (au) / healthy kids probiotic choc balls 50s 7.3 18.5 11.2
nature's way (au) / restore probiotic choc balls 60s 7.3 18.5 11.2
solgar / advanced acidophilus plus 7.3 18.5 11.2
optibac / for your cholesterol 7.3 27.1 19.8
jarrow formula / jarro-dophilus original 7.3 63.4 56.1
florastor / florastor 6.6 7.3 0.7
optibac / saccharomyces boulardii 6.6 7.3 0.7
organic 3 / yeastbiotic 6.6 7.3 0.7
spain (es) / muvagyn probiotico 6.6 15.8 9.2
bio-k+ 6.6 33 26.4
custom probiotics / six strain probiotic powder 6.6 61.4 54.8
jarrow formulas / jarro-dophilus mood 6 18.5 12.5
spain (es) / ns florabiotic instant 6 20.5 14.5
microbiome labs/ megasporebiotic 5.2 9.2 4
bayer / trubiotics daily probiotic 5.3 13.9 8.6
trubiotics / one a day 5.3 13.9 8.6
anabolic laboratories / probiotic complete 4.6 15.8 11.2
Jetson (US) / Mood Probiotics 4.6 18.5 13.9
just for tummies / live bacteria 4.7 33.7 29
bravo europe / freeze-dried bravo 4.7 33.7 29
cytoplan(uk) /dentavital bifidophilus 4.6 39.6 35
visbiome 4.6 56.1 51.5
spain (es) / vivomixx 4 51.5 47.5
up4 / adult 4 54.8 50.8
vitamin angels / just thrive 3.3 5.9 2.6
organic 3 / primal soil 3.3 5.9 2.6
reserveage nutrition / beautiflora 3.3 5.9 2.6
enviromedica terraflora sbo probiotic 3.3 5.9 2.6
corebiotic 3.3 5.9 2.6
klaire labs / biospora 3.3 5.9 2.6
perfect pass / perfect pass probiotic bacillus spore 3.3 5.9 2.6
global health trax / threelac 3.3 5.9 2.6
bio-botanical research / proflora4r restorative probiotic 3.3 5.9 2.6
activia drink 3.3 11.9 8.6
powerlabs (au) / ultra blend 3.3 20.5 17.2
jarrow formula / ideal bowel support® lp299v® 2.6 22.4 19.8
naturopathica (au) / gastrohealth probiotics 2 4 2
wakamoto (jp) / strong wakamoto w 1.9 5.9 4
Nu U (uk) /Bio-Cultures Complex 2 34.3 32.3
naturopathica (au) / gastrohealth women’s probiotic with cranberry 2 35 33
ferring / vsl#3 2 48.2 46.2
jarrow formulas / jarro-dophilus eps 2 52.8 50.8
bioglan bio (au) / happy probiotic 50 2 66 64
udo's choice /super 8 gold 2 74.6 72.6
reg'activ / immune & vitality 1.3 2.6 1.3
amy meyers / primal earth probiotic 0.7 3.3 2.6
microbiome labs /hu58 0.7 3.3 2.6
genestra brands® hm 0.6 31 30.4
spain (es) / profaes4 viajeros 0.6 31 30.4
spain (es) / profaes4 edad escolar 0.6 31 30.4
organic 3 / gutpro 0.6 60.7 60.1
canada (ca) / calmbiotic 0 8.6 8.6
spain (es) / suerobivos 0 10.6 10.6
culturelle / culturelle 0 10.6 10.6
spain (es) / bivos 0 10.6 10.6
spain (es) / kaleidon 0 10.6 10.6
digestive care 0 10.6 10.6
solgar / advanced multi-billion dophilus 0 34.3 34.3
solgar / advanced 40+ acidophilus 0 34.3 34.3
bravo europe / starter and complex 0 54.1 54.1
o'donnell / flora-balance -1.3 1.3 2.6
jamieson (can) / probiotic 10 bcfu -1.3 47.5 48.8
seed / female version -1.3 72.6 73.9
jarrow formulas / jarro-dophilus® ultra -1.3 73.3 74.6
quantum wellness / restora flora -1.3 92.4 93.7
organic 3 / primal gut -1.3 99 100.3
miyarisan (jp) / miyarisan -2 3.3 5.3
mwsb / candida yeast support -2 9.9 11.9
spain (es) / alflorex -2.7 2.6 5.3
natren / life start 2 (goat milk-based) -2.7 2.6 5.3
mutaflor / mutaflor -2.7 2.6 5.3
optibac / for daily immunity -2.6 9.9 12.5
gnc / ultra probiotic complex -2.7 24.4 27.1
klaire labs / ther-biotic factor 4 -2.7 25.7 28.4
Jetson / Gut Prep -3.3 4 7.3
renew life / ultimate flora -3.3 84.5 87.8
nature's bounty / probioti 10 -3.9 44.9 48.8
up4 / ultra -3.9 79.9 83.8
solaray / mycrobiome probiotic colon formula -4 80.5 84.5
bioglan bio (au) / happy probiotic 100 -3.9 86.5 90.4
garden of life / primal defense -3.9 87.8 91.7
shin biofermin (jp) /s -4.6 19.8 24.4
natren / healthy trinity probiotic -4.6 19.8 24.4
bioflorin (deu) / bioflorin -5.2 4 9.2
jarrow formulas / fem dophilus -5.3 16.5 21.8
spain (es) / aquilea intimus -5.3 16.5 21.8
blackmore (au) / probiotics+ womens flora balance -5.3 16.5 21.8
optibac / for women -5.3 16.5 21.8
jarrow formulas / fem-dophilus® -5.3 16.5 21.8
aor / probiotic-3 -6.6 12.5 19.1
custom probiotics / five strain bifidobacteria -6.6 21.1 27.7
klaire labs / target gb-x -6.6 45.5 52.1
nature's way (au) / restore probiotic 100 billion -6.6 98.3 104.9
naturopathica (au) / gastrohealth antacid -7.2 5.3 12.5
danactive drink -7.2 5.3 12.5
philips / colon health -7.2 20.5 27.7
wakamoto (jp) / wakamoto pharmaceutical intestinal drug -7.2 20.5 27.7
elixa / probiotic -9.2 85.8 95
vita miracle / ultra-30 probiotics -9.3 103.6 112.9
custom probiotics / b. lactis & b. bifidum probiotic powder -9.9 11.2 21.1
speer labs / emuaid first defense -9.9 23.8 33.7
renew life men's probiotic - ultimate -9.9 76.6 86.5
douglas laboratories / multi probiotic 40 billion -10.6 82.5 93.1
spain (es) / gastrus -11.2 6.6 17.8
spain (es) / reuteri gotas -11.2 6.6 17.8
spain (es) / casenbiotic -11.2 6.6 17.8
spain (es) / gum periobalance -11.2 6.6 17.8
fürstenmed / lacto-bifido -11.2 73.3 84.5
natren / bifido factor -11.9 6.6 18.5
bioray / cytoflora -11.8 83.2 95
hyperbiotics / pro-15 -11.9 101.6 113.5
Winclove Probiotics / Ecologic®825 -13.2 66.7 79.9
fairvital / microflora basic -15.2 47.5 62.7
newrhythm / probiotics 20 stains -15.2 100.3 115.5
Jetson (US) / Immunity Probiotics -27.7 46.2 73.9

No Known Impact

These appear to have no known direct impact. There is no reason to discontinue them if you are talking them

  1. goodbelly drink
  2. hyperbiotics / pro-dental
  3. natren / digesta-lac
  4. probiotic 3
  5. symbiopharm / symbioflor 1

Flavonoid Foods Suggested

These are a net positive impact -- Odds are that the dominant flavonoids are what is helping. They may be in other foods that have not been studied. Explore!

Flavonoids Suggested

These are a net positive impact -- see what foods they are in (the higher the better!)

Why "Source: Prefered in bulk and organic, with make your own capsules". First, few pre-capsulized supplements are organic, most have fillers and the cost per gram as prepared capsules can be 4x to 50x higher than in bulk. Many folks have reported things did not help until they change to a different brand with different fillers.

Items to decrease or stop

SubstanceProbability Estimate
thiamine hydrochloride (vitamin B1) 1
vitamin b3 (niacin) 1
Cyanocobalamin (Vitamin B-12) 0.986
Arbutin (polyphenol) 0.971
pyridoxine hydrochloride (vitamin B6) 0.971
retinoic acid (Vitamin A derivative) 0.971
diosmin (polyphenol) 0.971
folic acid (supplement Vitamin B9) 0.971
Hesperidin (polyphenol) 0.971
Guaiacol (polyphenol) 0.971
N-Acetyl Cysteine (NAC) 0.971
vitamin b7 biotin (supplement) (vitamin B7) 0.957
caffeine (coffee or non-herbal tea) 0.942
luteolin (flavonoid) 0.913
melatonin supplement 0.884
aspirin (acetylsalicylic acid) 0.768
garlic (allium sativum) 0.333

Contradictory Suggestions

I have seen lactobacillus rhamnosus gg (probiotics) being a TO TAKE and lactobacillus rhamnosus (probiotics) is to avoid. Why? Different studies have different results. Sometimes it is because of other factors (study done on healthy people in one case, on overweight people in the other case). One study may have measured the bacteria you are high in, the other did not. Similarly, one study may have measured the bacteria you are low in, the other did not. There is a forest of qualifications that are nearly impossibly complex to address, and if you try, it will often lack an objective decision that can be demonstrated ("I think...."). Where there are 'conflicts', my usual advice is to just omit it entirely from consideration. If you are taking it, keep taking it. It not, don't.


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