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The information on this site is from academic and research studies. Applicability to humans must be determined by a licensed medical professional.

Suggestions to counter the impact of mefloquine hydrochloride (prescription)

US These are suggestions that should be reviewed by a medical professional familar with you before implementing. Some suggestions may have adverse reactions with some conditions. The suggestions are built from a logical model using published research on humans and animals. The suggestions may not be applicable to humans.

Click on the substance to see what it modifies. For probiotic sources click here

Items to increase or take

;
Source: Prefered in bulk and organic, with make your own capsules
SubstanceProbability Estimate
inulin (prebiotic) ; 0.673
arabinoxylan oligosaccharides (prebiotic) ; 0.564
lactulose ; 0.4
resveratrol (grape seed/polyphenols/red wine) ; 0.4
ketogenic diet ; 0.309

Probiotic Mixtures

See this post on how to add more probiotic mixtures.

As always, probiotics should be reviewed by a knowledgable medical professional before starting.

Positive Impact

These have good impact with NO KNOWN RISK of bad impact. These should be your first choice

  1. symbiopharm / symbioflo 2 : impact 5.3
  2. nature's way (au) / adult vita gummies daily probiotic 80s : impact 3.3
  3. align / align : impact 3.3
  4. source naturals / duraflora : impact 3.3
  5. thorne / bacillus coagulansvet 60 caps : impact 3.3
  6. schiff / digestive advantage : impact 3.3
  7. daiichi sankyo healthcare (jp) / panlacmin tablet : impact 3.3
  8. reg'activ / immune & vitality : impact 2.6
  9. spain (es) / lactanza hereditum : impact 2.6
  10. enterogermina : impact 0.7

Mixed Impact

You want the highest NET value (Take - Avoid), when there are several with similar values. Take the one with the lowest avoid value.

Ideally you want Take/Avoid to be a 2:1 or higher ratio.

Commercial Probiotic NameNetTakeAvoid
nature's way (au) /restore probiotic bowel & colon health 30s 32.3 75.9 43.6
jarrow formulas / bifidus balance® + fos 31.7 59.4 27.7
naturopathica (au) / gastrohealth probiotic dairy free 50 billion 31.7 87.1 55.4
blackmore (au) / probiotics+ eczema relief 31 41.6 10.6
naturopathica (au) / gastrohealth probiotic dairy free 20 bcfu 31 68.6 37.6
nature's way (au) / restore probiotic daily health 90s 30.4 48.2 17.8
nature's way (au) / restore probiotic 30 billion 30s 30.4 48.2 17.8
naturopathica (au) / gastrohealth fibrepro 29.7 42.9 13.2
theramedix / probiotic 26.4 95 68.6
blackmores (au) / probiotics+ immune defence 25.8 60.1 34.3
blackmores (au) / probiotics + adults daily (90 capsules) 21.1 51.5 30.4
blackmore (au) / probiotics+ daily health 21.1 51.5 30.4
probiotic pur (de) / realdose nutrition 17.2 60.1 42.9
lifted naturals / mood boosting probiotic 15.8 60.7 44.9
naturopathica (au) / gastrohealth probiotic adults 50+ 14.5 32.3 17.8
up4 /women's 13.9 51.5 37.6
zint nutrition / probiotic collagen + 13.2 46.9 33.7
optibac / for every day 12.5 52.8 40.3
Realdose 12.5 55.4 42.9
optibac / for those on antibiotics 11.9 21.1 9.2
optibac / bifidobacteria & fibre 11.9 31.7 19.8
custom probiotics / four strain lactobacilli 11.2 44.2 33
blackmore (au) / probiotics+ bowel support 11.2 46.2 35
spain (es) / ns defenbiotic kids 10.6 21.8 11.2
Jetson / FIT 10.6 23.1 12.5
biospec / probiotic-5 9.2 36.3 27.1
naturopathica (au)/ gastrohealth probiotic daily care 8.6 20.5 11.9
optibac / for every day max 8.6 23.1 14.5
spain (es) / muvagyn probiotico 7.2 14.5 7.3
quality health(au)/ fridge free probiotic 25b 7.3 18.5 11.2
custom probiotics / d-lactate free probiotics powder 7.3 25.1 17.8
naturopathica (au) /gastrohealth probiotic ultimate daily care 100billion 7.2 55.4 48.2
spain (es) / ultralevura 6.6 7.9 1.3
spain (es) / axiboulardi 6.6 7.9 1.3
spain (es) / l3.1 6.6 27.7 21.1
bioglan bio (au/ happy probiotic 25 5.9 16.5 10.6
bioglan (au) / healthy kids probiotic choc balls 50s 5.9 16.5 10.6
nature's way (au) / restore probiotic choc balls 60s 5.9 16.5 10.6
solgar / advanced acidophilus plus 5.9 16.5 10.6
nature's instincts / ultra spore probiotic 5.3 7.9 2.6
natren / megadophilus 5.3 11.2 5.9
quality health (au) / fridge free* probiotic 60s 5.3 11.2 5.9
jarrow formulas / jarro-dophilus mood 5.3 16.5 11.2
optibac / for your cholesterol 5.3 25.1 19.8
young living/life 9 5.3 60.7 55.4
Jetson (US) / Mood Probiotics 4.6 16.5 11.9
seed / male version 4.7 60.1 55.4
microbiome labs/ megasporebiotic 4 7.3 3.3
bayer / trubiotics daily probiotic 4 11.9 7.9
activia drink 4 11.9 7.9
trubiotics / one a day 4 11.9 7.9
bio-k+ 4 29.7 25.7
cytoplan(uk) /dentavital bifidophilus 3.9 34.3 30.4
custom probiotics / six strain probiotic powder 4 54.8 50.8
jarrow formula / jarro-dophilus original 4 58.1 54.1
vinco / probiotic eight 65 4 58.1 54.1
florastor / florastor 3.3 4 0.7
optibac / saccharomyces boulardii 3.3 4 0.7
organic 3 / yeastbiotic 3.3 4 0.7
naturopathica (au) / gastrohealth probiotics 3.3 4 0.7
anabolic laboratories / probiotic complete 3.3 13.2 9.9
microbiome labs / restorflora 2.7 5.3 2.6
spain (es) / ns florabiotic instant 2.6 16.5 13.9
just for tummies / live bacteria 2.7 30.4 27.7
naturopathica (au) / gastrohealth women’s probiotic with cranberry 2.6 32.3 29.7
vitamin angels / just thrive 2 4 2
organic 3 / primal soil 2 4 2
reserveage nutrition / beautiflora 2 4 2
enviromedica terraflora sbo probiotic 2 4 2
corebiotic 2 4 2
klaire labs / biospora 2 4 2
perfect pass / perfect pass probiotic bacillus spore 2 4 2
global health trax / threelac 2 4 2
bio-botanical research / proflora4r restorative probiotic 2 4 2
1 md / complete probiotics platinum 2 77.2 75.2
powerlabs (au) / ultra blend 1.3 16.5 15.2
genestra brands® hm 1.3 28.4 27.1
spain (es) / profaes4 viajeros 1.3 28.4 27.1
spain (es) / profaes4 edad escolar 1.3 28.4 27.1
Nu U (uk) /Bio-Cultures Complex 1.3 29.7 28.4
jarrow formula / ideal bowel support® lp299v® 0.7 20.5 19.8
up4 / adult 0.7 48.2 47.5
jarrow formulas / jarro-dophilus eps 0.7 49.5 48.8
wakamoto (jp) / strong wakamoto w 0 4 4
bravo europe / freeze-dried bravo 0 27.7 27.7
amy meyers / primal earth probiotic -0.7 1.3 2
microbiome labs /hu58 -0.7 1.3 2
canada (ca) / calmbiotic -1.3 6.6 7.9
o'donnell / flora-balance -1.9 0.7 2.6
spain (es) / alflorex -2 2 4
natren / life start 2 (goat milk-based) -2 2 4
miyarisan (jp) / miyarisan -2 3.3 5.3
gnc / ultra probiotic complex -2 21.8 23.8
klaire labs / ther-biotic factor 4 -2 23.1 25.1
visbiome -2 48.2 50.2
mutaflor / mutaflor -2.7 2.6 5.3
organic 3 / gutpro -2.7 52.1 54.8
mwsb / candida yeast support -3.3 7.9 11.2
jarrow formulas / fem dophilus -3.3 15.8 19.1
spain (es) / aquilea intimus -3.3 15.8 19.1
blackmore (au) / probiotics+ womens flora balance -3.3 15.8 19.1
optibac / for women -3.3 15.8 19.1
jarrow formulas / fem-dophilus® -3.3 15.8 19.1
ferring / vsl#3 -3.3 42.2 45.5
spain (es) / vivomixx -3.3 42.9 46.2
spain (es) / suerobivos -4 6.6 10.6
culturelle / culturelle -4 6.6 10.6
spain (es) / bivos -4 6.6 10.6
spain (es) / kaleidon -4 6.6 10.6
digestive care -4 6.6 10.6
shin biofermin (jp) /s -3.9 17.2 21.1
natren / healthy trinity probiotic -3.9 17.2 21.1
bioglan bio (au) / happy probiotic 50 -4 58.7 62.7
udo's choice /super 8 gold -3.9 64.7 68.6
optibac / for daily immunity -4.6 7.9 12.5
bravo europe / starter and complex -4.6 44.9 49.5
Jetson / Gut Prep -5.3 2 7.3
bioflorin (deu) / bioflorin -5.2 4 9.2
aor / probiotic-3 -5.9 10.6 16.5
custom probiotics / five strain bifidobacteria -6 17.8 23.8
jamieson (can) / probiotic 10 bcfu -6 38.9 44.9
seed / female version -6 64 70
philips / colon health -6.6 16.5 23.1
wakamoto (jp) / wakamoto pharmaceutical intestinal drug -6.6 16.5 23.1
custom probiotics / b. lactis & b. bifidum probiotic powder -7.2 10.6 17.8
solgar / advanced multi-billion dophilus -7.3 26.4 33.7
solgar / advanced 40+ acidophilus -7.3 26.4 33.7
klaire labs / target gb-x -7.9 39.6 47.5
organic 3 / primal gut -8 85.1 93.1
jarrow formulas / jarro-dophilus® ultra -8.6 64 72.6
naturopathica (au) / gastrohealth antacid -9.2 3.3 12.5
danactive drink -9.2 3.3 12.5
natren / bifido factor -9.3 5.9 15.2
speer labs / emuaid first defense -9.3 21.1 30.4
nature's bounty / probioti 10 -9.3 37.6 46.9
solaray / mycrobiome probiotic colon formula -9.2 69.3 78.5
quantum wellness / restora flora -9.2 79.2 88.4
spain (es) / gastrus -9.9 5.9 15.8
spain (es) / reuteri gotas -9.9 5.9 15.8
spain (es) / casenbiotic -9.9 5.9 15.8
spain (es) / gum periobalance -9.9 5.9 15.8
up4 / ultra -9.9 70 79.9
renew life / ultimate flora -11.2 72.6 83.8
garden of life / primal defense -11.9 73.9 85.8
bioglan bio (au) / happy probiotic 100 -11.9 73.9 85.8
nature's way (au) / restore probiotic 100 billion -13.2 85.8 99
elixa / probiotic -13.9 75.2 89.1
bioray / cytoflora -16.5 71.9 88.4
vita miracle / ultra-30 probiotics -16.5 89.1 105.6
fürstenmed / lacto-bifido -17.2 62.7 79.9
douglas laboratories / multi probiotic 40 billion -17.9 68.6 86.5
fairvital / microflora basic -18.5 41.6 60.1
renew life men's probiotic - ultimate -18.5 64 82.5
hyperbiotics / pro-15 -18.5 87.1 105.6
Winclove Probiotics / Ecologic®825 -19.8 56.8 76.6
newrhythm / probiotics 20 stains -21.8 85.8 107.6
Jetson (US) / Immunity Probiotics -29 39.6 68.6

No Known Impact

These appear to have no known direct impact. There is no reason to discontinue them if you are talking them

  1. goodbelly drink
  2. hyperbiotics / pro-dental
  3. natren / digesta-lac
  4. probiotic 3
  5. symbiopharm / symbioflor 1

Flavonoid Foods Suggested

These are a net positive impact -- Odds are that the dominant flavonoids are what is helping. They may be in other foods that have not been studied. Explore!

Flavonoids Suggested

These are a net positive impact -- see what foods they are in (the higher the better!)

Why "Source: Prefered in bulk and organic, with make your own capsules". First, few pre-capsulized supplements are organic, most have fillers and the cost per gram as prepared capsules can be 4x to 50x higher than in bulk. Many folks have reported things did not help until they change to a different brand with different fillers.

Items to decrease or stop

SubstanceProbability Estimate
thiamine hydrochloride (vitamin B1) 1
Cyanocobalamin (Vitamin B-12) 0.982
diosmin (polyphenol) 0.964
folic acid (supplement Vitamin B9) 0.964
Guaiacol (polyphenol) 0.964
Hesperidin (polyphenol) 0.964
Arbutin (polyphenol) 0.964
N-Acetyl Cysteine (NAC) 0.964
pyridoxine hydrochloride (vitamin B6) 0.964
retinoic acid (Vitamin A derivative) 0.964
vitamin b7 biotin (supplement) (vitamin B7) 0.945
vitamin b3 (niacin) 0.927
caffeine (coffee or non-herbal tea) 0.927
luteolin (flavonoid) 0.909
melatonin supplement 0.855
aspirin (acetylsalicylic acid) 0.818
garlic (allium sativum) 0.418
chitosan (sugar) 0.327
tea 0.327

Contradictory Suggestions

I have seen lactobacillus rhamnosus gg (probiotics) being a TO TAKE and lactobacillus rhamnosus (probiotics) is to avoid. Why? Different studies have different results. Sometimes it is because of other factors (study done on healthy people in one case, on overweight people in the other case). One study may have measured the bacteria you are high in, the other did not. Similarly, one study may have measured the bacteria you are low in, the other did not. There is a forest of qualifications that are nearly impossibly complex to address, and if you try, it will often lack an objective decision that can be demonstrated ("I think...."). Where there are 'conflicts', my usual advice is to just omit it entirely from consideration. If you are taking it, keep taking it. It not, don't.


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