Suggestions to counter the impact of mefloquine hydrochloride (prescription)

US These are suggestions that should be reviewed by a medical professional familar with you before implementing. Some suggestions may have adverse reactions with some conditions. The suggestions are built from a logical model using published research on humans and animals. The suggestions may not be applicable to humans.

Click on the substance to see what it modifies. For probiotic sources click here

Items to increase or take

;
Source: Prefered in bulk and organic, with make your own capsules
SubstanceProbability Estimate
inulin (prebiotic) ; 0.733
resveratrol (grape seed/polyphenols/red wine) ; 0.606
arabinoxylan oligosaccharides (prebiotic) ; 0.6
resistant starch ; 0.509
almonds/ almond skins ; 0.418
lactulose ; 0.412
sesame cake/meal ; 0.4
daesiho-tang ; 0.4
ketogenic diet ; 0.37
magnesium ; 0.345
Slippery Elm ; 0.339
Vitamin B9 (Folate) ; 0.315
red wine ; 0.309

Probiotic Mixtures

See this post on how to add more probiotic mixtures.

As always, probiotics should be reviewed by a knowledgable medical professional before starting.

Positive Impact

These have good impact with NO KNOWN RISK of bad impact. These should be your first choice

  1. reg'activ / immune & vitality : impact 2.6
  2. Pädia GmbH (DE)/Mambiotic Kapseln : impact 2.6
  3. spain (es) / lactanza hereditum : impact 2.6
  4. enterogermina : impact 0.7

Mixed Impact

You want the highest NET value (Take - Avoid), when there are several with similar values. Take the one with the lowest avoid value.

Ideally you want Take/Avoid to be a 2:1 or higher ratio.

Commercial Probiotic NameNetTakeAvoid
nature's way (au) /restore probiotic bowel & colon health 30s 34.7 78.5 43.8
jarrow formulas / bifidus balance® + fos 34.6 62.5 27.9
naturopathica (au) / gastrohealth probiotic dairy free 50 billion 34.3 90.2 55.9
blackmore (au) / probiotics+ eczema relief 33.6 44.4 10.8
naturopathica (au) / gastrohealth probiotic dairy free 20 bcfu 33.5 71.3 37.8
nature's way (au) / restore probiotic daily health 90s 32.6 50.6 18
nature's way (au) / restore probiotic 30 billion 30s 32.6 50.6 18
naturopathica (au) / gastrohealth fibrepro 31.9 45.3 13.4
theramedix / probiotic 27.5 98.3 70.8
blackmores (au) / probiotics+ immune defence 27.3 62.5 35.2
probiotic pur (de) / realdose nutrition 25.3 69.5 44.2
blackmores (au) / probiotics + adults daily (90 capsules) 23.3 53.9 30.6
blackmore (au) / probiotics+ daily health 23.3 53.9 30.6
Realdose 19.4 63.6 44.2
blackmore (au) / probiotics+ bowel support 19.2 56.8 37.6
lifted naturals / mood boosting probiotic 16.5 61.4 44.9
Thryve Inside/ L.Reu,Rham,Casi; B.Lactis 15.4 66.7 51.3
naturopathica (au) / gastrohealth probiotic adults 50+ 15 32.8 17.8
up4 /women's 14.5 52.1 37.6
zint nutrition / probiotic collagen + 13.8 47.5 33.7
spain (es) / ultralevura 13.7 15.2 1.5
spain (es) / axiboulardi 13.7 15.2 1.5
optibac / for every day 12.6 53.5 40.9
optibac / for those on antibiotics 12.4 21.6 9.2
optibac / bifidobacteria & fibre 12.1 31.9 19.8
nature's instincts / ultra spore probiotic 11.8 15.8 4
spain (es) / ns defenbiotic kids 11 22.2 11.2
florastor / florastor 10.5 11.2 0.7
optibac / saccharomyces boulardii 10.5 11.2 0.7
organic 3 / yeastbiotic 10.5 11.2 0.7
custom probiotics / four strain lactobacilli 10.6 44.9 34.3
microbiome labs / restorflora 9.9 12.5 2.6
Jetson / FIT 9.9 23.8 13.9
naturopathica (au)/ gastrohealth probiotic daily care 8.8 20.9 12.1
optibac / for every day max 8.6 23.1 14.5
biospec / probiotic-5 7.9 37.6 29.7
spain (es) / muvagyn probiotico 7.7 15 7.3
naturopathica (au) /gastrohealth probiotic ultimate daily care 100billion 7.7 56.1 48.4
quality health(au)/ fridge free probiotic 25b 7.3 18.5 11.2
CustomProbiotics.com / L. Rhamnosus Probiotic Powder 7 10.3 3.3
optibac / for your cholesterol 6.8 26.6 19.8
spain (es) / l3.1 6.8 27.9 21.1
custom probiotics / d-lactate free probiotics powder 6.4 25.5 19.1
bioglan bio (au/ happy probiotic 25 5.9 16.5 10.6
bioglan (au) / healthy kids probiotic choc balls 50s 5.9 16.5 10.6
nature's way (au) / restore probiotic choc balls 60s 5.9 16.5 10.6
solgar / advanced acidophilus plus 5.9 16.5 10.6
jarrow formulas / jarro-dophilus mood 5.7 16.9 11.2
natren / megadophilus 5.3 11.2 5.9
CustomProbiotics.com / L. Acidophilus Probiotic Powder 5.3 11.2 5.9
quality health (au) / fridge free* probiotic 60s 5.3 11.2 5.9
HLH BIOPHARMA(DE) / LACTOBACT ® AAD 5.3 25.1 19.8
Jetson (US) / Mood Probiotics 5 16.9 11.9
jarrow formula / jarro-dophilus original 5.1 59.2 54.1
symbiopharm / symbioflo 2 4.9 5.3 0.4
bio-k+ 4.4 30.1 25.7
seed / male version 4.1 63.1 59
bayer / trubiotics daily probiotic 4 11.9 7.9
activia drink 4 11.9 7.9
trubiotics / one a day 4 11.9 7.9
young living/life 9 4 61.4 57.4
cytoplan(uk) /dentavital bifidophilus 3.8 34.8 31
microbiome labs/ megasporebiotic 3.3 7.9 4.6
anabolic laboratories / probiotic complete 3.3 13.2 9.9
spain (es) / ns florabiotic instant 3.3 17.2 13.9
vinco / probiotic eight 65 3.3 58.7 55.4
naturopathica (au) / gastrohealth probiotics 3.1 4 0.9
just for tummies / live bacteria 3.1 30.8 27.7
nature's way (au) / adult vita gummies daily probiotic 80s 2.7 4 1.3
align / align 2.7 4 1.3
source naturals / duraflora 2.7 4 1.3
thorne / bacillus coagulansvet 60 caps 2.7 4 1.3
schiff / digestive advantage 2.7 4 1.3
daiichi sankyo healthcare (jp) / panlacmin tablet 2.7 4 1.3
custom probiotics / six strain probiotic powder 2.6 55.4 52.8
powerlabs (au) / ultra blend 2 17.2 15.2
naturopathica (au) / gastrohealth women’s probiotic with cranberry 2 35.2 33.2
jarrow formulas / jarro-dophilus eps 1.8 50.6 48.8
vitamin angels / just thrive 1.3 4.6 3.3
organic 3 / primal soil 1.3 4.6 3.3
reserveage nutrition / beautiflora 1.3 4.6 3.3
enviromedica terraflora sbo probiotic 1.3 4.6 3.3
corebiotic 1.3 4.6 3.3
klaire labs / biospora 1.3 4.6 3.3
perfect pass / perfect pass probiotic bacillus spore 1.3 4.6 3.3
global health trax / threelac 1.3 4.6 3.3
bio-botanical research / proflora4r restorative probiotic 1.3 4.6 3.3
jarrow formula / ideal bowel support® lp299v® 0.9 20.7 19.8
CustomProbiotics.com / L. Plantarum Probiotic Powder 0.9 20.7 19.8
HLH BIOPHARMA(DE) / LACTOBACT ® LDL-CONTROL 0.9 20.7 19.8
CustomProbiotics.com / L. Gasseri Probiotic Powder 0.6 4.6 4
CustomProbiotics.com / B. Lactis Probiotic Powder 0.7 5.3 4.6
Sanogermina / AB-Kolicare 0.7 6.6 5.9
CustomProbiotics.com / B. Longum Probiotic Powder 0.7 6.6 5.9
genestra brands® hm 0.7 28.4 27.7
spain (es) / profaes4 viajeros 0.7 28.4 27.7
spain (es) / profaes4 edad escolar 0.7 28.4 27.7
up4 / adult 0.2 48.4 48.2
1 md / complete probiotics platinum 0 78.5 78.5
Nu U (uk) /Bio-Cultures Complex -0.3 30.1 30.4
amy meyers / primal earth probiotic -0.7 1.3 2
microbiome labs /hu58 -0.7 1.3 2
bravo europe / freeze-dried bravo -0.8 28.2 29
CustomProbiotics.com / B. Breve Probiotic Powder -1.3 0.7 2
wakamoto (jp) / strong wakamoto w -1.3 4 5.3
canada (ca) / calmbiotic -1.3 6.6 7.9
Thryve L.PCasei Th1, L.PCasei Th2,L.Ferm IBF1, L.acidoph -1.3 17.2 18.5
visbiome -1.8 48.4 50.2
o'donnell / flora-balance -1.9 0.7 2.6
CustomProbiotics.com / B. Infantis Probiotic Powder -2 2 4
spain (es) / alflorex -2 2 4
natren / life start 2 (goat milk-based) -2 2 4
miyarisan (jp) / miyarisan -2.2 3.3 5.5
CustomProbiotics.com / L. Salivarius Probiotic Powder -2.7 2.6 5.3
gnc / ultra probiotic complex -2.6 21.8 24.4
klaire labs / ther-biotic factor 4 -2.6 23.1 25.7
HLH BIOPHARMA(DE) / LACTOBACT ® METABOLIC -2.9 57.4 60.3
ferring / vsl#3 -3 42.5 45.5
spain (es) / vivomixx -3.1 43.1 46.2
mutaflor / mutaflor -3.3 2.6 5.9
optibac / for daily immunity -3.3 9.2 12.5
bioglan bio (au) / happy probiotic 50 -3.3 59.4 62.7
spain (es) / suerobivos -3.8 6.8 10.6
culturelle / culturelle -3.8 6.8 10.6
spain (es) / bivos -3.8 6.8 10.6
spain (es) / kaleidon -3.8 6.8 10.6
digestive care -3.8 6.8 10.6
jarrow formulas / fem dophilus -4 18.7 22.7
spain (es) / aquilea intimus -4 18.7 22.7
blackmore (au) / probiotics+ womens flora balance -4 18.7 22.7
optibac / for women -4 18.7 22.7
jarrow formulas / fem-dophilus® -4 18.7 22.7
mwsb / candida yeast support -4.2 8.6 12.8
organic 3 / gutpro -4.4 52.4 56.8
shin biofermin (jp) /s -4.6 17.2 21.8
natren / healthy trinity probiotic -4.6 17.2 21.8
ASEA VIA / BIOME -4.6 74.6 79.2
udo's choice /super 8 gold -5.3 65.3 70.6
Jetson / Gut Prep -5.5 2 7.5
bioflorin (deu) / bioflorin -5.5 4 9.5
aor / probiotic-3 -6.1 10.6 16.7
HLH BIOPHARMA(DE) / LACTOBACT ® FORTE -6.2 12.5 18.7
bravo europe / starter and complex -6.2 45.3 51.5
custom probiotics / five strain bifidobacteria -6.6 17.8 24.4
solgar / advanced multi-billion dophilus -7.1 26.6 33.7
solgar / advanced 40+ acidophilus -7.1 26.6 33.7
philips / colon health -7.3 16.5 23.8
wakamoto (jp) / wakamoto pharmaceutical intestinal drug -7.3 16.5 23.8
OMNi-BiOTiC®/ TRAVEL -7.3 59.4 66.7
seed / female version -7.2 67.8 75
jamieson (can) / probiotic 10 bcfu -7.5 39.4 46.9
CustomProbiotics.com / L. Casei Probiotic Powder -7.9 8.6 16.5
custom probiotics / b. lactis & b. bifidum probiotic powder -7.9 10.6 18.5
HLH BIOPHARMA(DE) / LACTOBACT ® 60PLUS -7.9 51.5 59.4
Seeking Health / Probiota HistaminX -8.4 41.1 49.5
jarrow formulas / jarro-dophilus® ultra -8.8 65.1 73.9
CustomProbiotics.com / L. Paracasei Probiotic Powder -9.2 3.3 12.5
naturopathica (au) / gastrohealth antacid -9.2 3.3 12.5
danactive drink -9.2 3.3 12.5
organic 3 / primal gut -9.2 85.8 95
customprobiotics.com / B. Bifidum Probiotic Powder -9.9 5.9 15.8
natren / bifido factor -9.9 5.9 15.8
klaire labs / target gb-x -9.9 39.6 49.5
up4 / ultra -9.9 70.6 80.5
speer labs / emuaid first defense -10.1 21.1 31.2
OMNi-BiOTiC®/ 10 AAD -10.2 68.6 78.8
nature's bounty / probioti 10 -10.6 37.6 48.2
quantum wellness / restora flora -10.5 79.9 90.4
solaray / mycrobiome probiotic colon formula -10.7 70 80.7
spain (es) / gastrus -11 8.4 19.4
spain (es) / reuteri gotas -11 8.4 19.4
spain (es) / casenbiotic -11 8.4 19.4
CustomProbiotics.com / L. Reuteri Probiotic Powder -11 8.4 19.4
spain (es) / gum periobalance -11 8.4 19.4
renew life / ultimate flora -12.5 73.3 85.8
ecology_allergycare -13.2 33 46.2
bioglan bio (au) / happy probiotic 100 -13.2 74.6 87.8
garden of life / primal defense -13.2 74.6 87.8
HLH BIOPHARMA(DE) / LACTOBACT ® PREMIUM -15.2 59.4 74.6
nature's way (au) / restore probiotic 100 billion -15.4 89.5 104.9
elixa / probiotic -16.3 78.3 94.6
fürstenmed / lacto-bifido -18.4 63.4 81.8
bioray / cytoflora -18.9 75 93.9
fairvital / microflora basic -19.4 44.2 63.6
douglas laboratories / multi probiotic 40 billion -19.5 68.9 88.4
vita miracle / ultra-30 probiotics -19.6 92.8 112.4
renew life men's probiotic - ultimate -20.3 64.2 84.5
HLH BIOPHARMA(DE) / LACTOBACT ® OMNI FOS -20.7 32.3 53
hyperbiotics / pro-15 -20.9 90.2 111.1
Winclove Probiotics / Ecologic®825 -21.5 57 78.5
newrhythm / probiotics 20 stains -23.8 89.5 113.3
Jetson (US) / Immunity Probiotics -30.8 42 72.8

No Known Impact

These appear to have no known direct impact. There is no reason to discontinue them if you are talking them

  1. CustomProbiotics.com / L. Brevis Probiotic Powder
  2. CustomProbiotics.com / L. Bulgaricus Probiotic Powder
  3. CustomProbiotics.com / L. Lactis Probiotic Powder
  4. CustomProbiotics.com / S. Thermophilus Probiotic Powder
  5. goodbelly drink
  6. hyperbiotics / pro-dental
  7. natren / digesta-lac
  8. probiotic 3
  9. symbiopharm / symbioflor 1
  10. Thryve/Ken's Recommendations
  11. Tryve/Ken's Recommendations

Flavonoid Foods Suggested

These are a net positive impact -- Odds are that the dominant flavonoids are what is helping. They may be in other foods that have not been studied. Explore!

Flavonoids Suggested

These are a net positive impact -- see what foods they are in (the higher the better!)

Why "Source: Prefered in bulk and organic, with make your own capsules". First, few pre-capsulized supplements are organic, most have fillers and the cost per gram as prepared capsules can be 4x to 50x higher than in bulk. Many folks have reported things did not help until they change to a different brand with different fillers.

Items to decrease or stop

SubstanceProbability Estimate
thiamine hydrochloride (vitamin B1) 1
Cyanocobalamin (Vitamin B-12) 0.982
retinoic acid (Vitamin A derivative) 0.964
Arbutin (polyphenol) 0.964
diosmin (polyphenol) 0.964
folic acid (supplement Vitamin B9) 0.964
Hesperidin (polyphenol) 0.964
pyridoxine hydrochloride (vitamin B6) 0.964
Guaiacol (polyphenol) 0.964
N-Acetyl Cysteine (NAC) 0.964
caffeine (coffee or non-herbal tea) 0.927
vitamin b3 (niacin) 0.927
vitamin b7 biotin (supplement) (vitamin B7) 0.927
luteolin (flavonoid) 0.909
melatonin supplement 0.855
Vitamin C (ascorbic acid) 0.855
aspirin (acetylsalicylic acid) 0.818
garlic (allium sativum) 0.418
tea 0.327
lactobacillus reuteri (probiotics) 0.303

Contradictory Suggestions

I have seen lactobacillus rhamnosus gg (probiotics) being a TO TAKE and lactobacillus rhamnosus (probiotics) is to avoid. Why? Different studies have different results. Sometimes it is because of other factors (study done on healthy people in one case, on overweight people in the other case). One study may have measured the bacteria you are high in, the other did not. Similarly, one study may have measured the bacteria you are low in, the other did not. There is a forest of qualifications that are nearly impossibly complex to address, and if you try, it will often lack an objective decision that can be demonstrated ("I think...."). Where there are 'conflicts', my usual advice is to just omit it entirely from consideration. If you are taking it, keep taking it. It not, don't.


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