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The information on this site is from academic and research studies. Applicability to humans must be determined by a licensed medical professional.

Suggestions to counter the impact of cyclobenzaprine hydrochloride (prescription)

US These are suggestions that should be reviewed by a medical professional familar with you before implementing. Some suggestions may have adverse reactions with some conditions. The suggestions are built from a logical model using published research on humans and animals. The suggestions may not be applicable to humans.

Click on the substance to see what it modifies. For probiotic sources click here

Items to increase or take

;
Source: Prefered in bulk and organic, with make your own capsules
SubstanceProbability Estimate
arabinoxylan oligosaccharides (prebiotic) ; 0.583
inulin (prebiotic) ; 0.533
lactulose ; 0.383
resistant starch ; 0.35
ketogenic diet ; 0.3
mediterranean diet ; 0.3
red wine ; 0.3

Probiotic Mixtures

See this post on how to add more probiotic mixtures.

As always, probiotics should be reviewed by a knowledgable medical professional before starting.

Positive Impact

These have good impact with NO KNOWN RISK of bad impact. These should be your first choice

  1. symbiopharm / symbioflo 2 : impact 4
  2. nature's way (au) / adult vita gummies daily probiotic 80s : impact 4
  3. align / align : impact 4
  4. source naturals / duraflora : impact 4
  5. thorne / bacillus coagulansvet 60 caps : impact 4
  6. schiff / digestive advantage : impact 4
  7. daiichi sankyo healthcare (jp) / panlacmin tablet : impact 4
  8. enterogermina : impact 1.3
  9. spain (es) / lactanza hereditum : impact 1.3

Mixed Impact

You want the highest NET value (Take - Avoid), when there are several with similar values. Take the one with the lowest avoid value.

Ideally you want Take/Avoid to be a 2:1 or higher ratio.

Commercial Probiotic NameNetTakeAvoid
nature's way (au) /restore probiotic bowel & colon health 30s 34.4 73.3 38.9
naturopathica (au) / gastrohealth probiotic dairy free 50 billion 31.7 83.8 52.1
naturopathica (au) / gastrohealth probiotic dairy free 20 bcfu 31 64.7 33.7
theramedix / probiotic 29.7 95.7 66
naturopathica (au) / gastrohealth fibrepro 27.7 41.6 13.9
probiotic pur (de) / realdose nutrition 27.7 65.3 37.6
nature's way (au) / restore probiotic daily health 90s 27 45.5 18.5
nature's way (au) / restore probiotic 30 billion 30s 27 45.5 18.5
blackmore (au) / probiotics+ eczema relief 23.8 36.3 12.5
Realdose 23.1 60.7 37.6
blackmores (au) / probiotics + adults daily (90 capsules) 21.1 50.8 29.7
blackmore (au) / probiotics+ daily health 21.1 50.8 29.7
jarrow formulas / bifidus balance® + fos 19.1 52.1 33
blackmores (au) / probiotics+ immune defence 17.8 54.1 36.3
custom probiotics / four strain lactobacilli 13.8 42.2 28.4
up4 /women's 13.8 47.5 33.7
zint nutrition / probiotic collagen + 12.6 41.6 29
lifted naturals / mood boosting probiotic 12.5 52.8 40.3
naturopathica (au) / gastrohealth probiotic adults 50+ 11.8 29 17.2
biospec / probiotic-5 11.2 34.3 23.1
blackmore (au) / probiotics+ bowel support 10.6 46.2 35.6
naturopathica (au) /gastrohealth probiotic ultimate daily care 100billion 10.5 54.1 43.6
nature's instincts / ultra spore probiotic 9.9 13.2 3.3
spain (es) / l3.1 9.9 26.4 16.5
optibac / for those on antibiotics 9.3 18.5 9.2
spain (es) / ultralevura 8.6 11.2 2.6
spain (es) / axiboulardi 8.6 11.2 2.6
optibac / for your cholesterol 8.6 23.8 15.2
vinco / probiotic eight 65 7.9 56.1 48.2
1 md / complete probiotics platinum 7.9 78.5 70.6
microbiome labs / restorflora 7.3 10.6 3.3
seed / male version 7.3 56.1 48.8
young living/life 9 7.2 58.7 51.5
florastor / florastor 6.6 7.3 0.7
optibac / saccharomyces boulardii 6.6 7.3 0.7
organic 3 / yeastbiotic 6.6 7.3 0.7
natren / megadophilus 6.6 11.9 5.3
quality health (au) / fridge free* probiotic 60s 6.6 11.9 5.3
visbiome 6.6 50.2 43.6
bioglan bio (au/ happy probiotic 25 5.9 15.8 9.9
bioglan (au) / healthy kids probiotic choc balls 50s 5.9 15.8 9.9
nature's way (au) / restore probiotic choc balls 60s 5.9 15.8 9.9
solgar / advanced acidophilus plus 5.9 15.8 9.9
custom probiotics / d-lactate free probiotics powder 6 23.8 17.8
spain (es) / vivomixx 5.9 45.5 39.6
bayer / trubiotics daily probiotic 4.6 12.5 7.9
trubiotics / one a day 4.6 12.5 7.9
anabolic laboratories / probiotic complete 4.6 14.5 9.9
naturopathica (au)/ gastrohealth probiotic daily care 4.6 17.8 13.2
optibac / for every day max 4.6 18.5 13.9
up4 / adult 4.6 47.5 42.9
optibac / for every day 4.6 49.5 44.9
custom probiotics / six strain probiotic powder 4.6 52.1 47.5
spain (es) / muvagyn probiotico 3.9 12.5 8.6
quality health(au)/ fridge free probiotic 25b 4 15.2 11.2
jarrow formula / ideal bowel support® lp299v® 3.9 19.1 15.2
bio-k+ 4 28.4 24.4
vitamin angels / just thrive 3.3 5.9 2.6
organic 3 / primal soil 3.3 5.9 2.6
reserveage nutrition / beautiflora 3.3 5.9 2.6
enviromedica terraflora sbo probiotic 3.3 5.9 2.6
corebiotic 3.3 5.9 2.6
klaire labs / biospora 3.3 5.9 2.6
perfect pass / perfect pass probiotic bacillus spore 3.3 5.9 2.6
global health trax / threelac 3.3 5.9 2.6
bio-botanical research / proflora4r restorative probiotic 3.3 5.9 2.6
microbiome labs/ megasporebiotic 3.3 7.3 4
jarrow formula / jarro-dophilus original 3.3 52.1 48.8
jarrow formulas / jarro-dophilus mood 2.7 13.9 11.2
spain (es) / ns florabiotic instant 2.6 15.8 13.2
naturopathica (au) / gastrohealth probiotics 2 4 2
wakamoto (jp) / strong wakamoto w 1.9 5.9 4
bravo europe / freeze-dried bravo 1.9 29 27.1
just for tummies / live bacteria 1.9 29 27.1
cytoplan(uk) /dentavital bifidophilus 2 33.7 31.7
spain (es) / ns defenbiotic kids 1.3 13.2 11.9
optibac / bifidobacteria & fibre 1.3 24.4 23.1
Nu U (uk) /Bio-Cultures Complex 1.3 29 27.7
bioglan bio (au) / happy probiotic 50 1.4 56.8 55.4
udo's choice /super 8 gold 1.3 65.3 64
amy meyers / primal earth probiotic 0.7 3.3 2.6
microbiome labs /hu58 0.7 3.3 2.6
mwsb / candida yeast support 0.7 9.9 9.2
powerlabs (au) / ultra blend 0.7 17.2 16.5
ferring / vsl#3 0.7 39.6 38.9
reg'activ / immune & vitality 0 1.3 1.3
canada (ca) / calmbiotic 0 7.3 7.3
spain (es) / suerobivos 0 9.2 9.2
culturelle / culturelle 0 9.2 9.2
spain (es) / bivos 0 9.2 9.2
spain (es) / kaleidon 0 9.2 9.2
digestive care 0 9.2 9.2
naturopathica (au) / gastrohealth women’s probiotic with cranberry 0 28.4 28.4
solgar / advanced multi-billion dophilus 0 30.4 30.4
solgar / advanced 40+ acidophilus 0 30.4 30.4
jarrow formulas / jarro-dophilus eps 0 44.2 44.2
miyarisan (jp) / miyarisan -0.7 3.3 4
organic 3 / gutpro -0.7 50.8 51.5
o'donnell / flora-balance -1.3 1.3 2.6
activia drink -1.3 6.6 7.9
optibac / for daily immunity -1.3 9.9 11.2
seed / female version -1.3 61.4 62.7
spain (es) / alflorex -2 2.6 4.6
natren / life start 2 (goat milk-based) -2 2.6 4.6
bravo europe / starter and complex -1.9 46.9 48.8
solaray / mycrobiome probiotic colon formula -1.9 70 71.9
bioflorin (deu) / bioflorin -2.6 4 6.6
gnc / ultra probiotic complex -2.6 21.8 24.4
mutaflor / mutaflor -3.3 2 5.3
aor / probiotic-3 -3.3 12.5 15.8
genestra brands® hm -3.3 24.4 27.7
spain (es) / profaes4 viajeros -3.3 24.4 27.7
spain (es) / profaes4 edad escolar -3.3 24.4 27.7
jamieson (can) / probiotic 10 bcfu -3.3 41.6 44.9
jarrow formulas / jarro-dophilus® ultra -3.3 62 65.3
renew life / ultimate flora -3.3 73.9 77.2
bioglan bio (au) / happy probiotic 100 -3.3 75.9 79.2
shin biofermin (jp) /s -3.9 18.5 22.4
natren / healthy trinity probiotic -3.9 18.5 22.4
up4 / ultra -4 69.3 73.3
garden of life / primal defense -4 77.2 81.2
quantum wellness / restora flora -4 79.2 83.2
organic 3 / primal gut -3.9 84.5 88.4
naturopathica (au) / gastrohealth antacid -5.9 5.3 11.2
danactive drink -5.9 5.3 11.2
jarrow formulas / fem dophilus -6 12.5 18.5
spain (es) / aquilea intimus -6 12.5 18.5
blackmore (au) / probiotics+ womens flora balance -6 12.5 18.5
optibac / for women -6 12.5 18.5
jarrow formulas / fem-dophilus® -6 12.5 18.5
custom probiotics / five strain bifidobacteria -5.9 18.5 24.4
philips / colon health -6 19.1 25.1
wakamoto (jp) / wakamoto pharmaceutical intestinal drug -6 19.1 25.1
renew life men's probiotic - ultimate -5.9 69.3 75.2
douglas laboratories / multi probiotic 40 billion -6 75.2 81.2
nature's way (au) / restore probiotic 100 billion -5.9 84.5 90.4
klaire labs / ther-biotic factor 4 -6.6 19.1 25.7
speer labs / emuaid first defense -6.6 22.4 29
nature's bounty / probioti 10 -6.6 38.3 44.9
vita miracle / ultra-30 probiotics -6.6 91.1 97.7
Winclove Probiotics / Ecologic®825 -7.2 60.1 67.3
elixa / probiotic -7.2 74.6 81.8
spain (es) / gastrus -8.6 5.9 14.5
spain (es) / reuteri gotas -8.6 5.9 14.5
spain (es) / casenbiotic -8.6 5.9 14.5
spain (es) / gum periobalance -8.6 5.9 14.5
bioray / cytoflora -8.5 73.3 81.8
custom probiotics / b. lactis & b. bifidum probiotic powder -9.2 9.9 19.1
klaire labs / target gb-x -9.3 38.9 48.2
hyperbiotics / pro-15 -9.2 89.1 98.3
fairvital / microflora basic -9.9 42.2 52.1
fürstenmed / lacto-bifido -9.9 64 73.9
natren / bifido factor -10.6 6.6 17.2
newrhythm / probiotics 20 stains -10.6 89.1 99.7

No Known Impact

These appear to have no known direct impact. There is no reason to discontinue them if you are talking them

  1. goodbelly drink
  2. hyperbiotics / pro-dental
  3. natren / digesta-lac
  4. probiotic 3
  5. symbiopharm / symbioflor 1

Flavonoid Foods Suggested

These are a net positive impact -- Odds are that the dominant flavonoids are what is helping. They may be in other foods that have not been studied. Explore!

Flavonoids Suggested

These are a net positive impact -- see what foods they are in (the higher the better!)

Why "Source: Prefered in bulk and organic, with make your own capsules". First, few pre-capsulized supplements are organic, most have fillers and the cost per gram as prepared capsules can be 4x to 50x higher than in bulk. Many folks have reported things did not help until they change to a different brand with different fillers.

Items to decrease or stop

SubstanceProbability Estimate
thiamine hydrochloride (vitamin B1) 1
vitamin b3 (niacin) 1
Cyanocobalamin (Vitamin B-12) 0.983
Arbutin (polyphenol) 0.967
diosmin (polyphenol) 0.967
folic acid (supplement Vitamin B9) 0.967
Guaiacol (polyphenol) 0.967
Hesperidin (polyphenol) 0.967
N-Acetyl Cysteine (NAC) 0.967
pyridoxine hydrochloride (vitamin B6) 0.967
retinoic acid (Vitamin A derivative) 0.967
melatonin supplement 0.95
vitamin b7 biotin (supplement) (vitamin B7) 0.95
caffeine (coffee or non-herbal tea) 0.933
luteolin (flavonoid) 0.9
aspirin (acetylsalicylic acid) 0.733
garlic (allium sativum) 0.35
chitosan (sugar) 0.333
tea 0.3

Contradictory Suggestions

I have seen lactobacillus rhamnosus gg (probiotics) being a TO TAKE and lactobacillus rhamnosus (probiotics) is to avoid. Why? Different studies have different results. Sometimes it is because of other factors (study done on healthy people in one case, on overweight people in the other case). One study may have measured the bacteria you are high in, the other did not. Similarly, one study may have measured the bacteria you are low in, the other did not. There is a forest of qualifications that are nearly impossibly complex to address, and if you try, it will often lack an objective decision that can be demonstrated ("I think...."). Where there are 'conflicts', my usual advice is to just omit it entirely from consideration. If you are taking it, keep taking it. It not, don't.


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