Suggestions to counter the impact of spiperone (prescription)

US These are suggestions that should be reviewed by a medical professional familar with you before implementing. Some suggestions may have adverse reactions with some conditions. The suggestions are built from a logical model using published research on humans and animals. The suggestions may not be applicable to humans.

Click on the substance to see what it modifies. For probiotic sources click here

Items to increase or take

;
Source: Prefered in bulk and organic, with make your own capsules
SubstanceProbability Estimate
inulin (prebiotic) ; 0.596
arabinoxylan oligosaccharides (prebiotic) ; 0.586
resistant starch ; 0.495
resveratrol (grape seed/polyphenols/red wine) ; 0.444
lactulose ; 0.404
ketogenic diet ; 0.399
almonds/ almond skins ; 0.348
red wine ; 0.348
sesame cake/meal ; 0.333
daesiho-tang ; 0.333
Slippery Elm ; 0.323
saccharomyces boulardii (probiotics) ; 0.318

Probiotic Mixtures

See this post on how to add more probiotic mixtures.

As always, probiotics should be reviewed by a knowledgable medical professional before starting.

Positive Impact

These have good impact with NO KNOWN RISK of bad impact. These should be your first choice

  1. Pädia GmbH (DE)/Mambiotic Kapseln : impact 2.6
  2. spain (es) / lactanza hereditum : impact 2.6
  3. enterogermina : impact 1.3

Mixed Impact

You want the highest NET value (Take - Avoid), when there are several with similar values. Take the one with the lowest avoid value.

Ideally you want Take/Avoid to be a 2:1 or higher ratio.

Commercial Probiotic NameNetTakeAvoid
nature's way (au) /restore probiotic bowel & colon health 30s 37.6 84 46.4
naturopathica (au) / gastrohealth probiotic dairy free 50 billion 37.2 97 59.8
naturopathica (au) / gastrohealth probiotic dairy free 20 bcfu 35.7 75.5 39.8
probiotic pur (de) / realdose nutrition 33 80.3 47.3
blackmore (au) / probiotics+ eczema relief 32.3 45.1 12.8
naturopathica (au) / gastrohealth fibrepro 32.2 46.9 14.7
nature's way (au) / restore probiotic daily health 90s 32.1 52.1 20
nature's way (au) / restore probiotic 30 billion 30s 32.1 52.1 20
jarrow formulas / bifidus balance® + fos 30.6 65.1 34.5
theramedix / probiotic 28.8 105.8 77
Realdose 27.1 74.4 47.3
blackmores (au) / probiotics + adults daily (90 capsules) 24.8 57.4 32.6
blackmore (au) / probiotics+ daily health 24.8 57.4 32.6
blackmores (au) / probiotics+ immune defence 22.9 62.7 39.8
blackmore (au) / probiotics+ bowel support 18.5 61.4 42.9
up4 /women's 16.5 57 40.5
nature's instincts / ultra spore probiotic 16.3 21.1 4.8
lifted naturals / mood boosting probiotic 16.3 64.5 48.2
zint nutrition / probiotic collagen + 16 51 35
spain (es) / ultralevura 15.6 18.5 2.9
spain (es) / axiboulardi 15.6 18.5 2.9
custom probiotics / four strain lactobacilli 15.4 50.4 35
naturopathica (au) / gastrohealth probiotic adults 50+ 15.2 34.3 19.1
microbiome labs / restorflora 14.5 17.8 3.3
florastor / florastor 13.8 14.5 0.7
optibac / saccharomyces boulardii 13.8 14.5 0.7
organic 3 / yeastbiotic 13.8 14.5 0.7
optibac / for those on antibiotics 12.5 22.4 9.9
biospec / probiotic-5 12.3 42.9 30.6
Jetson / FIT 11.2 26.6 15.4
naturopathica (au) /gastrohealth probiotic ultimate daily care 100billion 11.3 62.3 51
optibac / for your cholesterol 9.5 29.3 19.8
spain (es) / l3.1 9.5 30.6 21.1
optibac / for every day 8.8 57.6 48.8
vinco / probiotic eight 65 8.8 65.6 56.8
jarrow formula / jarro-dophilus original 7.9 64 56.1
spain (es) / ns defenbiotic kids 7.7 20.2 12.5
custom probiotics / d-lactate free probiotics powder 7.7 28.8 21.1
optibac / bifidobacteria & fibre 7.5 31.9 24.4
spain (es) / muvagyn probiotico 6.8 16.3 9.5
naturopathica (au)/ gastrohealth probiotic daily care 6.9 21.6 14.7
optibac / for every day max 6.8 22 15.2
young living/life 9 6.8 68.2 61.4
spain (es) / ns florabiotic instant 6.6 21.1 14.5
CustomProbiotics.com / L. Rhamnosus Probiotic Powder 6.3 10.3 4
seed / male version 6.4 68 61.6
natren / megadophilus 6.2 12.1 5.9
CustomProbiotics.com / L. Acidophilus Probiotic Powder 6.2 12.1 5.9
quality health (au) / fridge free* probiotic 60s 6.2 12.1 5.9
bioglan bio (au/ happy probiotic 25 6.2 17.4 11.2
bioglan (au) / healthy kids probiotic choc balls 50s 6.2 17.4 11.2
nature's way (au) / restore probiotic choc balls 60s 6.2 17.4 11.2
solgar / advanced acidophilus plus 6.2 17.4 11.2
bio-k+ 5.9 32.3 26.4
quality health(au)/ fridge free probiotic 25b 5.5 17.4 11.9
jarrow formulas / jarro-dophilus mood 5.1 17.6 12.5
Jetson (US) / Mood Probiotics 5 18.9 13.9
symbiopharm / symbioflo 2 4.9 5.3 0.4
custom probiotics / six strain probiotic powder 4.8 61.6 56.8
1 md / complete probiotics platinum 4.4 88.7 84.3
bayer / trubiotics daily probiotic 4.2 12.8 8.6
trubiotics / one a day 4.2 12.8 8.6
just for tummies / live bacteria 4 33 29
microbiome labs/ megasporebiotic 3.7 9.2 5.5
jarrow formulas / jarro-dophilus eps 3.8 54.6 50.8
anabolic laboratories / probiotic complete 3.5 14.7 11.2
jarrow formula / ideal bowel support® lp299v® 3.5 23.3 19.8
CustomProbiotics.com / L. Plantarum Probiotic Powder 3.5 23.3 19.8
nature's way (au) / adult vita gummies daily probiotic 80s 3.1 4.6 1.5
align / align 3.1 4.6 1.5
source naturals / duraflora 3.1 4.6 1.5
thorne / bacillus coagulansvet 60 caps 3.1 4.6 1.5
schiff / digestive advantage 3.1 4.6 1.5
daiichi sankyo healthcare (jp) / panlacmin tablet 3.1 4.6 1.5
visbiome 3.1 54.6 51.5
powerlabs (au) / ultra blend 2.8 20 17.2
bravo europe / freeze-dried bravo 2.6 33 30.4
vitamin angels / just thrive 2.4 6.6 4.2
organic 3 / primal soil 2.4 6.6 4.2
reserveage nutrition / beautiflora 2.4 6.6 4.2
enviromedica terraflora sbo probiotic 2.4 6.6 4.2
corebiotic 2.4 6.6 4.2
klaire labs / biospora 2.4 6.6 4.2
perfect pass / perfect pass probiotic bacillus spore 2.4 6.6 4.2
global health trax / threelac 2.4 6.6 4.2
bio-botanical research / proflora4r restorative probiotic 2.4 6.6 4.2
spain (es) / vivomixx 2.4 49.9 47.5
bioglan bio (au) / happy probiotic 50 2.2 66.2 64
cytoplan(uk) /dentavital bifidophilus 2 37.6 35.6
naturopathica (au) / gastrohealth probiotics 1.8 4 2.2
up4 / adult 1.7 53.2 51.5
reg'activ / immune & vitality 1.6 2.9 1.3
activia drink 1.3 9.9 8.6
naturopathica (au) / gastrohealth women’s probiotic with cranberry 0.9 36.1 35.2
amy meyers / primal earth probiotic 0.7 3.3 2.6
microbiome labs /hu58 0.7 3.3 2.6
wakamoto (jp) / strong wakamoto w 0.6 5.9 5.3
CustomProbiotics.com / B. Longum Probiotic Powder 0.7 7.3 6.6
CustomProbiotics.com / L. Gasseri Probiotic Powder 0.4 5.9 5.5
spain (es) / suerobivos 0.2 10.8 10.6
culturelle / culturelle 0.2 10.8 10.6
spain (es) / bivos 0.2 10.8 10.6
spain (es) / kaleidon 0.2 10.8 10.6
digestive care 0.2 10.8 10.6
CustomProbiotics.com / B. Lactis Probiotic Powder 0 5.3 5.3
ferring / vsl#3 -0.2 46 46.2
CustomProbiotics.com / L. Salivarius Probiotic Powder -0.7 4.6 5.3
Nu U (uk) /Bio-Cultures Complex -0.6 33.7 34.3
solgar / advanced multi-billion dophilus -0.9 33.4 34.3
solgar / advanced 40+ acidophilus -0.9 33.4 34.3
CustomProbiotics.com / L. Brevis Probiotic Powder -1.1 0.2 1.3
udo's choice /super 8 gold -1.1 73.5 74.6
o'donnell / flora-balance -1.3 1.3 2.6
canada (ca) / calmbiotic -1.3 7.3 8.6
optibac / for daily immunity -1.3 11.2 12.5
seed / female version -1.3 77 78.3
mwsb / candida yeast support -1.7 10.6 12.3
ASEA VIA / BIOME -1.7 84.3 86
CustomProbiotics.com / B. Breve Probiotic Powder -1.9 0.7 2.6
jarrow formulas / jarro-dophilus® ultra -2 73.9 75.9
miyarisan (jp) / miyarisan -2.2 3.3 5.5
CustomProbiotics.com / B. Infantis Probiotic Powder -2.7 2.6 5.3
spain (es) / alflorex -2.7 2.6 5.3
natren / life start 2 (goat milk-based) -2.7 2.6 5.3
Jetson / Gut Prep -2.8 4 6.8
genestra brands® hm -3.1 27.9 31
spain (es) / profaes4 viajeros -3.1 27.9 31
spain (es) / profaes4 edad escolar -3.1 27.9 31
mutaflor / mutaflor -3.3 2.6 5.9
bravo europe / starter and complex -4 52.1 56.1
organic 3 / gutpro -4 58.3 62.3
bioflorin (deu) / bioflorin -4.1 4 8.1
gnc / ultra probiotic complex -4.4 23.3 27.7
jarrow formulas / fem dophilus -5.3 18.7 24
spain (es) / aquilea intimus -5.3 18.7 24
blackmore (au) / probiotics+ womens flora balance -5.3 18.7 24
optibac / for women -5.3 18.7 24
jarrow formulas / fem-dophilus® -5.3 18.7 24
jamieson (can) / probiotic 10 bcfu -5.3 45.5 50.8
aor / probiotic-3 -5.5 12.5 18
Seeking Health / Probiota HistaminX -5.8 47.7 53.5
up4 / ultra -5.7 78.8 84.5
solaray / mycrobiome probiotic colon formula -5.8 79.6 85.4
shin biofermin (jp) /s -6.4 18.7 25.1
natren / healthy trinity probiotic -6.4 18.7 25.1
renew life / ultimate flora -6.4 83.4 89.8
organic 3 / primal gut -6.4 96.1 102.5
CustomProbiotics.com / L. Casei Probiotic Powder -6.6 9.9 16.5
klaire labs / ther-biotic factor 4 -6.6 22.4 29
quantum wellness / restora flora -6.6 89.3 95.9
garden of life / primal defense -6.8 86.9 93.7
bioglan bio (au) / happy probiotic 100 -7 85.4 92.4
CustomProbiotics.com / L. Paracasei Probiotic Powder -7.2 5.3 12.5
naturopathica (au) / gastrohealth antacid -7.2 5.3 12.5
danactive drink -7.2 5.3 12.5
nature's bounty / probioti 10 -8.2 42 50.2
custom probiotics / five strain bifidobacteria -8.6 19.8 28.4
philips / colon health -9.5 19.1 28.6
wakamoto (jp) / wakamoto pharmaceutical intestinal drug -9.5 19.1 28.6
nature's way (au) / restore probiotic 100 billion -10.1 99.7 109.8
custom probiotics / b. lactis & b. bifidum probiotic powder -10.6 11.2 21.8
speer labs / emuaid first defense -10.5 22.7 33.2
klaire labs / target gb-x -11.4 42.7 54.1
spain (es) / gastrus -11.6 8.4 20
spain (es) / reuteri gotas -11.6 8.4 20
spain (es) / casenbiotic -11.6 8.4 20
CustomProbiotics.com / L. Reuteri Probiotic Powder -11.6 8.4 20
spain (es) / gum periobalance -11.6 8.4 20
ecology_allergycare -11.7 37.8 49.5
customprobiotics.com / B. Bifidum Probiotic Powder -12.5 6.6 19.1
natren / bifido factor -12.5 6.6 19.1
elixa / probiotic -12.7 86.5 99.2
fürstenmed / lacto-bifido -13.2 73.3 86.5
renew life men's probiotic - ultimate -13.4 75 88.4
vita miracle / ultra-30 probiotics -13.9 104.9 118.8
douglas laboratories / multi probiotic 40 billion -14.1 81.2 95.3
Winclove Probiotics / Ecologic®825 -15.4 66.4 81.8
bioray / cytoflora -15.4 83.8 99.2
hyperbiotics / pro-15 -15.6 102.3 117.9
fairvital / microflora basic -16.1 48.8 64.9
newrhythm / probiotics 20 stains -17.2 103.6 120.8
Jetson (US) / Immunity Probiotics -29.9 46.9 76.8

No Known Impact

These appear to have no known direct impact. There is no reason to discontinue them if you are talking them

  1. CustomProbiotics.com / L. Bulgaricus Probiotic Powder
  2. CustomProbiotics.com / L. Lactis Probiotic Powder
  3. CustomProbiotics.com / S. Thermophilus Probiotic Powder
  4. goodbelly drink
  5. hyperbiotics / pro-dental
  6. natren / digesta-lac
  7. probiotic 3
  8. symbiopharm / symbioflor 1

Flavonoid Foods Suggested

These are a net positive impact -- Odds are that the dominant flavonoids are what is helping. They may be in other foods that have not been studied. Explore!

Flavonoids Suggested

These are a net positive impact -- see what foods they are in (the higher the better!)

Why "Source: Prefered in bulk and organic, with make your own capsules". First, few pre-capsulized supplements are organic, most have fillers and the cost per gram as prepared capsules can be 4x to 50x higher than in bulk. Many folks have reported things did not help until they change to a different brand with different fillers.

Items to decrease or stop

SubstanceProbability Estimate
thiamine hydrochloride (vitamin B1) 1
vitamin b3 (niacin) 1
Cyanocobalamin (Vitamin B-12) 0.985
retinoic acid (Vitamin A derivative) 0.97
Arbutin (polyphenol) 0.97
diosmin (polyphenol) 0.97
folic acid (supplement Vitamin B9) 0.97
Hesperidin (polyphenol) 0.97
pyridoxine hydrochloride (vitamin B6) 0.97
Guaiacol (polyphenol) 0.97
N-Acetyl Cysteine (NAC) 0.97
caffeine (coffee or non-herbal tea) 0.939
vitamin b7 biotin (supplement) (vitamin B7) 0.939
luteolin (flavonoid) 0.909
melatonin supplement 0.879
Vitamin C (ascorbic acid) 0.879
aspirin (acetylsalicylic acid) 0.758
garlic (allium sativum) 0.348

Contradictory Suggestions

I have seen lactobacillus rhamnosus gg (probiotics) being a TO TAKE and lactobacillus rhamnosus (probiotics) is to avoid. Why? Different studies have different results. Sometimes it is because of other factors (study done on healthy people in one case, on overweight people in the other case). One study may have measured the bacteria you are high in, the other did not. Similarly, one study may have measured the bacteria you are low in, the other did not. There is a forest of qualifications that are nearly impossibly complex to address, and if you try, it will often lack an objective decision that can be demonstrated ("I think...."). Where there are 'conflicts', my usual advice is to just omit it entirely from consideration. If you are taking it, keep taking it. It not, don't.


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