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The information on this site is from academic and research studies. Applicability to humans must be determined by a licensed medical professional.

Suggestions to counter the impact of itraconazole (prescription)

US These are suggestions that should be reviewed by a medical professional familar with you before implementing. Some suggestions may have adverse reactions with some conditions. The suggestions are built from a logical model using published research on humans and animals. The suggestions may not be applicable to humans.

Click on the substance to see what it modifies. For probiotic sources click here

Items to increase or take

;
Source: Prefered in bulk and organic, with make your own capsules
SubstanceProbability Estimate
inulin (prebiotic) ; 0.552
arabinoxylan oligosaccharides (prebiotic) ; 0.537
lactulose ; 0.388
ketogenic diet ; 0.343
red wine ; 0.313

Probiotic Mixtures

See this post on how to add more probiotic mixtures.

As always, probiotics should be reviewed by a knowledgable medical professional before starting.

Positive Impact

These have good impact with NO KNOWN RISK of bad impact. These should be your first choice

  1. symbiopharm / symbioflo 2 : impact 5.3
  2. nature's way (au) / adult vita gummies daily probiotic 80s : impact 4
  3. align / align : impact 4
  4. source naturals / duraflora : impact 4
  5. thorne / bacillus coagulansvet 60 caps : impact 4
  6. schiff / digestive advantage : impact 4
  7. daiichi sankyo healthcare (jp) / panlacmin tablet : impact 4
  8. spain (es) / lactanza hereditum : impact 2.6
  9. enterogermina : impact 1.3

Mixed Impact

You want the highest NET value (Take - Avoid), when there are several with similar values. Take the one with the lowest avoid value.

Ideally you want Take/Avoid to be a 2:1 or higher ratio.

Commercial Probiotic NameNetTakeAvoid
nature's way (au) /restore probiotic bowel & colon health 30s 36.3 82.5 46.2
naturopathica (au) / gastrohealth probiotic dairy free 50 billion 34.3 93.7 59.4
naturopathica (au) / gastrohealth probiotic dairy free 20 bcfu 33 72.6 39.6
blackmore (au) / probiotics+ eczema relief 30.4 42.9 12.5
naturopathica (au) / gastrohealth fibrepro 30.4 44.9 14.5
nature's way (au) / restore probiotic daily health 90s 30.4 50.2 19.8
nature's way (au) / restore probiotic 30 billion 30s 30.4 50.2 19.8
jarrow formulas / bifidus balance® + fos 29.7 62.7 33
theramedix / probiotic 29 103.6 74.6
probiotic pur (de) / realdose nutrition 25.1 70.6 45.5
blackmores (au) / probiotics+ immune defence 23.8 62.7 38.9
blackmores (au) / probiotics + adults daily (90 capsules) 21.8 54.1 32.3
blackmore (au) / probiotics+ daily health 21.8 54.1 32.3
Realdose 20.5 66 45.5
lifted naturals / mood boosting probiotic 17.8 66 48.2
naturopathica (au) / gastrohealth probiotic adults 50+ 15.9 35 19.1
custom probiotics / four strain lactobacilli 15.1 48.8 33.7
up4 /women's 15.1 55.4 40.3
zint nutrition / probiotic collagen + 14.5 49.5 35
biospec / probiotic-5 13.2 40.9 27.7
optibac / for those on antibiotics 11.9 21.8 9.9
Jetson / FIT 11.8 25.7 13.9
blackmore (au) / probiotics+ bowel support 11.2 51.5 40.3
optibac / for every day 11.2 58.1 46.9
optibac / bifidobacteria & fibre 10.6 33.7 23.1
custom probiotics / d-lactate free probiotics powder 9.9 29.7 19.8
naturopathica (au) /gastrohealth probiotic ultimate daily care 100billion 9.9 60.7 50.8
nature's instincts / ultra spore probiotic 9.2 12.5 3.3
spain (es) / ns defenbiotic kids 9.3 21.8 12.5
optibac / for every day max 8.6 23.8 15.2
spain (es) / l3.1 8.6 29.7 21.1
vinco / probiotic eight 65 8.6 64 55.4
young living/life 9 8.6 68 59.4
spain (es) / ultralevura 8 10.6 2.6
spain (es) / axiboulardi 8 10.6 2.6
naturopathica (au)/ gastrohealth probiotic daily care 7.9 22.4 14.5
quality health(au)/ fridge free probiotic 25b 7.2 19.1 11.9
optibac / for your cholesterol 7.3 27.1 19.8
1 md / complete probiotics platinum 7.3 87.8 80.5
microbiome labs / restorflora 6.6 9.9 3.3
spain (es) / muvagyn probiotico 6.6 15.8 9.2
florastor / florastor 5.9 6.6 0.7
optibac / saccharomyces boulardii 5.9 6.6 0.7
organic 3 / yeastbiotic 5.9 6.6 0.7
natren / megadophilus 6 11.9 5.9
quality health (au) / fridge free* probiotic 60s 6 11.9 5.9
bioglan bio (au/ happy probiotic 25 6 17.2 11.2
bioglan (au) / healthy kids probiotic choc balls 50s 6 17.2 11.2
nature's way (au) / restore probiotic choc balls 60s 6 17.2 11.2
solgar / advanced acidophilus plus 6 17.2 11.2
jarrow formulas / jarro-dophilus mood 6 18.5 12.5
jarrow formula / jarro-dophilus original 5.9 62 56.1
seed / male version 5.9 65.3 59.4
microbiome labs/ megasporebiotic 5.2 9.2 4
bio-k+ 5.3 31.7 26.4
custom probiotics / six strain probiotic powder 5.3 60.1 54.8
Jetson (US) / Mood Probiotics 4.6 18.5 13.9
spain (es) / ns florabiotic instant 4.6 19.1 14.5
bayer / trubiotics daily probiotic 3.9 12.5 8.6
trubiotics / one a day 3.9 12.5 8.6
vitamin angels / just thrive 3.3 5.9 2.6
organic 3 / primal soil 3.3 5.9 2.6
reserveage nutrition / beautiflora 3.3 5.9 2.6
enviromedica terraflora sbo probiotic 3.3 5.9 2.6
corebiotic 3.3 5.9 2.6
klaire labs / biospora 3.3 5.9 2.6
perfect pass / perfect pass probiotic bacillus spore 3.3 5.9 2.6
global health trax / threelac 3.3 5.9 2.6
bio-botanical research / proflora4r restorative probiotic 3.3 5.9 2.6
activia drink 3.3 11.9 8.6
anabolic laboratories / probiotic complete 3.3 14.5 11.2
just for tummies / live bacteria 3.3 32.3 29
cytoplan(uk) /dentavital bifidophilus 3.3 38.3 35
visbiome 3.3 54.8 51.5
jarrow formula / ideal bowel support® lp299v® 2.6 22.4 19.8
up4 / adult 2.7 53.5 50.8
naturopathica (au) / gastrohealth probiotics 2 4 2
wakamoto (jp) / strong wakamoto w 1.9 5.9 4
powerlabs (au) / ultra blend 1.9 19.1 17.2
bravo europe / freeze-dried bravo 2 31 29
jarrow formulas / jarro-dophilus eps 2 52.8 50.8
reg'activ / immune & vitality 1.3 2.6 1.3
spain (es) / vivomixx 1.3 48.8 47.5
amy meyers / primal earth probiotic 0.7 3.3 2.6
microbiome labs /hu58 0.7 3.3 2.6
Nu U (uk) /Bio-Cultures Complex 0.7 33 32.3
organic 3 / gutpro 0.6 60.7 60.1
udo's choice /super 8 gold 0.7 73.3 72.6
canada (ca) / calmbiotic 0 8.6 8.6
naturopathica (au) / gastrohealth women’s probiotic with cranberry 0 33 33
genestra brands® hm -0.7 29.7 30.4
spain (es) / profaes4 viajeros -0.7 29.7 30.4
spain (es) / profaes4 edad escolar -0.7 29.7 30.4
ferring / vsl#3 -0.7 45.5 46.2
bioglan bio (au) / happy probiotic 50 -0.6 63.4 64
o'donnell / flora-balance -1.3 1.3 2.6
spain (es) / suerobivos -1.4 9.2 10.6
culturelle / culturelle -1.4 9.2 10.6
spain (es) / bivos -1.4 9.2 10.6
spain (es) / kaleidon -1.4 9.2 10.6
digestive care -1.4 9.2 10.6
miyarisan (jp) / miyarisan -2 3.3 5.3
mwsb / candida yeast support -2 9.9 11.9
seed / female version -2 71.9 73.9
spain (es) / alflorex -2.7 2.6 5.3
natren / life start 2 (goat milk-based) -2.7 2.6 5.3
mutaflor / mutaflor -2.7 2.6 5.3
klaire labs / ther-biotic factor 4 -2.7 25.7 28.4
bravo europe / starter and complex -2.6 51.5 54.1
Jetson / Gut Prep -3.3 4 7.3
optibac / for daily immunity -3.9 8.6 12.5
gnc / ultra probiotic complex -4 23.1 27.1
solgar / advanced multi-billion dophilus -3.9 30.4 34.3
solgar / advanced 40+ acidophilus -3.9 30.4 34.3
jamieson (can) / probiotic 10 bcfu -3.9 44.9 48.8
jarrow formulas / jarro-dophilus® ultra -4 70.6 74.6
quantum wellness / restora flora -3.9 89.8 93.7
organic 3 / primal gut -3.9 96.4 100.3
bioflorin (deu) / bioflorin -5.2 4 9.2
jarrow formulas / fem dophilus -6 15.8 21.8
spain (es) / aquilea intimus -6 15.8 21.8
blackmore (au) / probiotics+ womens flora balance -6 15.8 21.8
optibac / for women -6 15.8 21.8
jarrow formulas / fem-dophilus® -6 15.8 21.8
shin biofermin (jp) /s -5.9 18.5 24.4
natren / healthy trinity probiotic -5.9 18.5 24.4
renew life / ultimate flora -6 81.8 87.8
aor / probiotic-3 -6.6 12.5 19.1
custom probiotics / five strain bifidobacteria -6.6 21.1 27.7
nature's bounty / probioti 10 -6.6 42.2 48.8
up4 / ultra -6.6 77.2 83.8
solaray / mycrobiome probiotic colon formula -6.6 77.9 84.5
bioglan bio (au) / happy probiotic 100 -6.6 83.8 90.4
garden of life / primal defense -6.6 85.1 91.7
philips / colon health -7.2 20.5 27.7
wakamoto (jp) / wakamoto pharmaceutical intestinal drug -7.2 20.5 27.7
klaire labs / target gb-x -7.9 44.2 52.1
naturopathica (au) / gastrohealth antacid -8.5 4 12.5
danactive drink -8.5 4 12.5
custom probiotics / b. lactis & b. bifidum probiotic powder -9.9 11.2 21.1
nature's way (au) / restore probiotic 100 billion -9.9 95 104.9
speer labs / emuaid first defense -11.3 22.4 33.7
elixa / probiotic -11.2 83.8 95
spain (es) / gastrus -11.9 5.9 17.8
spain (es) / reuteri gotas -11.9 5.9 17.8
spain (es) / casenbiotic -11.9 5.9 17.8
spain (es) / gum periobalance -11.9 5.9 17.8
natren / bifido factor -11.9 6.6 18.5
fürstenmed / lacto-bifido -12.6 71.9 84.5
renew life men's probiotic - ultimate -12.6 73.9 86.5
vita miracle / ultra-30 probiotics -12.6 100.3 112.9
douglas laboratories / multi probiotic 40 billion -13.2 79.9 93.1
bioray / cytoflora -13.8 81.2 95
hyperbiotics / pro-15 -15.2 98.3 113.5
fairvital / microflora basic -15.8 46.9 62.7
Winclove Probiotics / Ecologic®825 -15.9 64 79.9
newrhythm / probiotics 20 stains -18.5 97 115.5
Jetson (US) / Immunity Probiotics -31 42.9 73.9

No Known Impact

These appear to have no known direct impact. There is no reason to discontinue them if you are talking them

  1. goodbelly drink
  2. hyperbiotics / pro-dental
  3. natren / digesta-lac
  4. probiotic 3
  5. symbiopharm / symbioflor 1

Flavonoid Foods Suggested

These are a net positive impact -- Odds are that the dominant flavonoids are what is helping. They may be in other foods that have not been studied. Explore!

Flavonoids Suggested

These are a net positive impact -- see what foods they are in (the higher the better!)

Why "Source: Prefered in bulk and organic, with make your own capsules". First, few pre-capsulized supplements are organic, most have fillers and the cost per gram as prepared capsules can be 4x to 50x higher than in bulk. Many folks have reported things did not help until they change to a different brand with different fillers.

Items to decrease or stop

SubstanceProbability Estimate
thiamine hydrochloride (vitamin B1) 1
vitamin b3 (niacin) 1
Cyanocobalamin (Vitamin B-12) 0.985
Arbutin (polyphenol) 0.97
pyridoxine hydrochloride (vitamin B6) 0.97
retinoic acid (Vitamin A derivative) 0.97
diosmin (polyphenol) 0.97
folic acid (supplement Vitamin B9) 0.97
Hesperidin (polyphenol) 0.97
Guaiacol (polyphenol) 0.97
N-Acetyl Cysteine (NAC) 0.97
vitamin b7 biotin (supplement) (vitamin B7) 0.955
caffeine (coffee or non-herbal tea) 0.94
luteolin (flavonoid) 0.925
melatonin supplement 0.881
aspirin (acetylsalicylic acid) 0.761
garlic (allium sativum) 0.343

Contradictory Suggestions

I have seen lactobacillus rhamnosus gg (probiotics) being a TO TAKE and lactobacillus rhamnosus (probiotics) is to avoid. Why? Different studies have different results. Sometimes it is because of other factors (study done on healthy people in one case, on overweight people in the other case). One study may have measured the bacteria you are high in, the other did not. Similarly, one study may have measured the bacteria you are low in, the other did not. There is a forest of qualifications that are nearly impossibly complex to address, and if you try, it will often lack an objective decision that can be demonstrated ("I think...."). Where there are 'conflicts', my usual advice is to just omit it entirely from consideration. If you are taking it, keep taking it. It not, don't.


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