Suggestions to counter the impact of itraconazole (prescription)

US These are suggestions that should be reviewed by a medical professional familar with you before implementing. Some suggestions may have adverse reactions with some conditions. The suggestions are built from a logical model using published research on humans and animals. The suggestions may not be applicable to humans.

Click on the substance to see what it modifies. For probiotic sources click here

Items to increase or take

;
Source: Prefered in bulk and organic, with make your own capsules
SubstanceProbability Estimate
inulin (prebiotic) ; 0.587
arabinoxylan oligosaccharides (prebiotic) ; 0.547
resistant starch ; 0.443
resveratrol (grape seed/polyphenols/red wine) ; 0.438
lactulose ; 0.398
ketogenic diet ; 0.393
almonds/ almond skins ; 0.358
sesame cake/meal ; 0.328
daesiho-tang ; 0.328
red wine ; 0.328
Slippery Elm ; 0.318

Probiotic Mixtures

See this post on how to add more probiotic mixtures.

As always, probiotics should be reviewed by a knowledgable medical professional before starting.

Positive Impact

These have good impact with NO KNOWN RISK of bad impact. These should be your first choice

  1. Pädia GmbH (DE)/Mambiotic Kapseln : impact 2.6
  2. spain (es) / lactanza hereditum : impact 2.6
  3. enterogermina : impact 1.3

Mixed Impact

You want the highest NET value (Take - Avoid), when there are several with similar values. Take the one with the lowest avoid value.

Ideally you want Take/Avoid to be a 2:1 or higher ratio.

Commercial Probiotic NameNetTakeAvoid
nature's way (au) /restore probiotic bowel & colon health 30s 38.7 85.1 46.4
naturopathica (au) / gastrohealth probiotic dairy free 50 billion 37 96.8 59.8
naturopathica (au) / gastrohealth probiotic dairy free 20 bcfu 35.4 75.2 39.8
probiotic pur (de) / realdose nutrition 33.4 80.7 47.3
blackmore (au) / probiotics+ eczema relief 32.3 45.1 12.8
naturopathica (au) / gastrohealth fibrepro 31.9 46.6 14.7
nature's way (au) / restore probiotic daily health 90s 31.9 51.9 20
nature's way (au) / restore probiotic 30 billion 30s 31.9 51.9 20
jarrow formulas / bifidus balance® + fos 31.9 65.1 33.2
theramedix / probiotic 29.9 106.9 77
Realdose 27.5 74.8 47.3
blackmores (au) / probiotics+ immune defence 24.7 64.5 39.8
blackmores (au) / probiotics + adults daily (90 capsules) 23.3 55.9 32.6
blackmore (au) / probiotics+ daily health 23.3 55.9 32.6
lifted naturals / mood boosting probiotic 19.3 67.5 48.2
blackmore (au) / probiotics+ bowel support 18.3 61.2 42.9
naturopathica (au) / gastrohealth probiotic adults 50+ 16.3 35.4 19.1
up4 /women's 16.3 56.8 40.5
zint nutrition / probiotic collagen + 15.8 50.8 35
nature's instincts / ultra spore probiotic 15.7 20.5 4.8
custom probiotics / four strain lactobacilli 15.2 50.2 35
spain (es) / ultralevura 14.9 17.8 2.9
spain (es) / axiboulardi 14.9 17.8 2.9
microbiome labs / restorflora 13.9 17.2 3.3
florastor / florastor 13.2 13.9 0.7
optibac / saccharomyces boulardii 13.2 13.9 0.7
organic 3 / yeastbiotic 13.2 13.9 0.7
optibac / for those on antibiotics 12.3 22.2 9.9
biospec / probiotic-5 12.3 42.9 30.6
optibac / for every day 11.2 58.7 47.5
Jetson / FIT 11 26.4 15.4
naturopathica (au) /gastrohealth probiotic ultimate daily care 100billion 11 62 51
optibac / bifidobacteria & fibre 10.8 33.9 23.1
spain (es) / ns defenbiotic kids 9.7 22.2 12.5
optibac / for your cholesterol 9.5 29.3 19.8
spain (es) / l3.1 9.5 30.6 21.1
custom probiotics / d-lactate free probiotics powder 9 30.1 21.1
optibac / for every day max 8.6 23.8 15.2
vinco / probiotic eight 65 8.5 65.3 56.8
naturopathica (au)/ gastrohealth probiotic daily care 8.2 22.9 14.7
young living/life 9 7.9 69.3 61.4
jarrow formula / jarro-dophilus original 7.7 63.8 56.1
quality health(au)/ fridge free probiotic 25b 7.2 19.1 11.9
spain (es) / muvagyn probiotico 6.8 16.3 9.5
CustomProbiotics.com / L. Rhamnosus Probiotic Powder 6.3 10.3 4
jarrow formulas / jarro-dophilus mood 6.4 18.9 12.5
seed / male version 6.2 69.1 62.9
natren / megadophilus 6 11.9 5.9
CustomProbiotics.com / L. Acidophilus Probiotic Powder 6 11.9 5.9
quality health (au) / fridge free* probiotic 60s 6 11.9 5.9
bioglan bio (au/ happy probiotic 25 6 17.2 11.2
bioglan (au) / healthy kids probiotic choc balls 50s 6 17.2 11.2
nature's way (au) / restore probiotic choc balls 60s 6 17.2 11.2
solgar / advanced acidophilus plus 6 17.2 11.2
bio-k+ 5.7 32.1 26.4
1 md / complete probiotics platinum 5.5 89.8 84.3
spain (es) / ns florabiotic instant 5.3 19.8 14.5
Jetson (US) / Mood Probiotics 5 18.9 13.9
symbiopharm / symbioflo 2 4.9 5.3 0.4
custom probiotics / six strain probiotic powder 4.6 61.4 56.8
microbiome labs/ megasporebiotic 4.4 9.9 5.5
visbiome 4.2 55.7 51.5
bayer / trubiotics daily probiotic 3.9 12.5 8.6
trubiotics / one a day 3.9 12.5 8.6
just for tummies / live bacteria 3.8 32.8 29
jarrow formulas / jarro-dophilus eps 3.8 54.6 50.8
jarrow formula / ideal bowel support® lp299v® 3.5 23.3 19.8
CustomProbiotics.com / L. Plantarum Probiotic Powder 3.5 23.3 19.8
activia drink 3.3 11.9 8.6
anabolic laboratories / probiotic complete 3.3 14.5 11.2
nature's way (au) / adult vita gummies daily probiotic 80s 3.1 4.6 1.5
align / align 3.1 4.6 1.5
source naturals / duraflora 3.1 4.6 1.5
thorne / bacillus coagulansvet 60 caps 3.1 4.6 1.5
schiff / digestive advantage 3.1 4.6 1.5
daiichi sankyo healthcare (jp) / panlacmin tablet 3.1 4.6 1.5
cytoplan(uk) /dentavital bifidophilus 3.1 38.7 35.6
up4 / adult 2.8 54.3 51.5
powerlabs (au) / ultra blend 2.6 19.8 17.2
vitamin angels / just thrive 2.4 6.6 4.2
organic 3 / primal soil 2.4 6.6 4.2
reserveage nutrition / beautiflora 2.4 6.6 4.2
enviromedica terraflora sbo probiotic 2.4 6.6 4.2
corebiotic 2.4 6.6 4.2
klaire labs / biospora 2.4 6.6 4.2
perfect pass / perfect pass probiotic bacillus spore 2.4 6.6 4.2
global health trax / threelac 2.4 6.6 4.2
bio-botanical research / proflora4r restorative probiotic 2.4 6.6 4.2
spain (es) / vivomixx 2.2 49.7 47.5
CustomProbiotics.com / B. Longum Probiotic Powder 2 8.6 6.6
naturopathica (au) / gastrohealth probiotics 1.8 4 2.2
reg'activ / immune & vitality 1.6 2.9 1.3
bravo europe / freeze-dried bravo 1.1 31.5 30.4
amy meyers / primal earth probiotic 0.7 3.3 2.6
microbiome labs /hu58 0.7 3.3 2.6
wakamoto (jp) / strong wakamoto w 0.6 5.9 5.3
bioglan bio (au) / happy probiotic 50 0.7 64.7 64
CustomProbiotics.com / L. Gasseri Probiotic Powder 0.4 5.9 5.5
ferring / vsl#3 0.2 46.4 46.2
CustomProbiotics.com / B. Lactis Probiotic Powder 0 5.3 5.3
canada (ca) / calmbiotic 0 8.6 8.6
udo's choice /super 8 gold 0 74.6 74.6
CustomProbiotics.com / L. Salivarius Probiotic Powder -0.7 4.6 5.3
naturopathica (au) / gastrohealth women’s probiotic with cranberry -0.6 35.9 36.5
organic 3 / gutpro -0.7 61.6 62.3
ASEA VIA / BIOME -0.6 85.4 86
Nu U (uk) /Bio-Cultures Complex -0.9 33.4 34.3
CustomProbiotics.com / L. Brevis Probiotic Powder -1.1 0.2 1.3
spain (es) / suerobivos -1.1 9.5 10.6
culturelle / culturelle -1.1 9.5 10.6
spain (es) / bivos -1.1 9.5 10.6
spain (es) / kaleidon -1.1 9.5 10.6
digestive care -1.1 9.5 10.6
o'donnell / flora-balance -1.3 1.3 2.6
genestra brands® hm -1.3 29.7 31
spain (es) / profaes4 viajeros -1.3 29.7 31
spain (es) / profaes4 edad escolar -1.3 29.7 31
CustomProbiotics.com / B. Breve Probiotic Powder -1.9 0.7 2.6
seed / female version -1.9 77.7 79.6
miyarisan (jp) / miyarisan -2.2 3.3 5.5
CustomProbiotics.com / B. Infantis Probiotic Powder -2.7 2.6 5.3
spain (es) / alflorex -2.7 2.6 5.3
natren / life start 2 (goat milk-based) -2.7 2.6 5.3
optibac / for daily immunity -2.6 9.9 12.5
mwsb / candida yeast support -3 10.6 13.6
mutaflor / mutaflor -3.3 2.6 5.9
klaire labs / ther-biotic factor 4 -3.3 25.7 29
jarrow formulas / jarro-dophilus® ultra -3.5 72.4 75.9
solgar / advanced multi-billion dophilus -3.7 30.6 34.3
solgar / advanced 40+ acidophilus -3.7 30.6 34.3
Jetson / Gut Prep -4.1 4 8.1
bravo europe / starter and complex -4.2 51.9 56.1
Seeking Health / Probiota HistaminX -4.4 49.1 53.5
gnc / ultra probiotic complex -4.6 23.1 27.7
organic 3 / primal gut -4.6 97.9 102.5
quantum wellness / restora flora -4.8 91.1 95.9
bioflorin (deu) / bioflorin -5.5 4 9.5
jamieson (can) / probiotic 10 bcfu -5.5 45.3 50.8
up4 / ultra -6 78.5 84.5
CustomProbiotics.com / L. Casei Probiotic Powder -6.6 9.9 16.5
shin biofermin (jp) /s -6.6 18.5 25.1
natren / healthy trinity probiotic -6.6 18.5 25.1
jarrow formulas / fem dophilus -6.6 18.7 25.3
spain (es) / aquilea intimus -6.6 18.7 25.3
blackmore (au) / probiotics+ womens flora balance -6.6 18.7 25.3
optibac / for women -6.6 18.7 25.3
jarrow formulas / fem-dophilus® -6.6 18.7 25.3
renew life / ultimate flora -6.6 83.2 89.8
aor / probiotic-3 -6.9 12.5 19.4
garden of life / primal defense -7 86.7 93.7
custom probiotics / five strain bifidobacteria -7.3 21.1 28.4
solaray / mycrobiome probiotic colon formula -7.3 79.4 86.7
bioglan bio (au) / happy probiotic 100 -7.3 85.1 92.4
nature's bounty / probioti 10 -7.7 42.5 50.2
philips / colon health -8.1 20.5 28.6
wakamoto (jp) / wakamoto pharmaceutical intestinal drug -8.1 20.5 28.6
CustomProbiotics.com / L. Paracasei Probiotic Powder -8.5 4 12.5
naturopathica (au) / gastrohealth antacid -8.5 4 12.5
danactive drink -8.5 4 12.5
klaire labs / target gb-x -9.7 44.4 54.1
custom probiotics / b. lactis & b. bifidum probiotic powder -10.6 11.2 21.8
nature's way (au) / restore probiotic 100 billion -11.7 99.4 111.1
ecology_allergycare -11.9 37.6 49.5
speer labs / emuaid first defense -12.1 22.4 34.5
customprobiotics.com / B. Bifidum Probiotic Powder -12.5 6.6 19.1
natren / bifido factor -12.5 6.6 19.1
spain (es) / gastrus -12.9 8.4 21.3
spain (es) / reuteri gotas -12.9 8.4 21.3
spain (es) / casenbiotic -12.9 8.4 21.3
CustomProbiotics.com / L. Reuteri Probiotic Powder -12.9 8.4 21.3
spain (es) / gum periobalance -12.9 8.4 21.3
elixa / probiotic -12.9 87.6 100.5
fürstenmed / lacto-bifido -13.2 73.3 86.5
renew life men's probiotic - ultimate -13.6 74.8 88.4
douglas laboratories / multi probiotic 40 billion -14.3 81 95.3
vita miracle / ultra-30 probiotics -15.4 104.7 120.1
bioray / cytoflora -15.6 84.9 100.5
fairvital / microflora basic -16 50.2 66.2
Winclove Probiotics / Ecologic®825 -16.9 64.9 81.8
hyperbiotics / pro-15 -17.1 102.1 119.2
newrhythm / probiotics 20 stains -19.4 102.7 122.1
Jetson (US) / Immunity Probiotics -32.8 45.3 78.1

No Known Impact

These appear to have no known direct impact. There is no reason to discontinue them if you are talking them

  1. CustomProbiotics.com / L. Bulgaricus Probiotic Powder
  2. CustomProbiotics.com / L. Lactis Probiotic Powder
  3. CustomProbiotics.com / S. Thermophilus Probiotic Powder
  4. goodbelly drink
  5. hyperbiotics / pro-dental
  6. natren / digesta-lac
  7. probiotic 3
  8. symbiopharm / symbioflor 1

Flavonoid Foods Suggested

These are a net positive impact -- Odds are that the dominant flavonoids are what is helping. They may be in other foods that have not been studied. Explore!

Flavonoids Suggested

These are a net positive impact -- see what foods they are in (the higher the better!)

Why "Source: Prefered in bulk and organic, with make your own capsules". First, few pre-capsulized supplements are organic, most have fillers and the cost per gram as prepared capsules can be 4x to 50x higher than in bulk. Many folks have reported things did not help until they change to a different brand with different fillers.

Items to decrease or stop

SubstanceProbability Estimate
thiamine hydrochloride (vitamin B1) 1
vitamin b3 (niacin) 1
Cyanocobalamin (Vitamin B-12) 0.985
retinoic acid (Vitamin A derivative) 0.97
Arbutin (polyphenol) 0.97
diosmin (polyphenol) 0.97
folic acid (supplement Vitamin B9) 0.97
Hesperidin (polyphenol) 0.97
pyridoxine hydrochloride (vitamin B6) 0.97
Guaiacol (polyphenol) 0.97
N-Acetyl Cysteine (NAC) 0.97
caffeine (coffee or non-herbal tea) 0.94
vitamin b7 biotin (supplement) (vitamin B7) 0.94
luteolin (flavonoid) 0.925
melatonin supplement 0.881
Vitamin C (ascorbic acid) 0.881
aspirin (acetylsalicylic acid) 0.761
garlic (allium sativum) 0.343

Contradictory Suggestions

I have seen lactobacillus rhamnosus gg (probiotics) being a TO TAKE and lactobacillus rhamnosus (probiotics) is to avoid. Why? Different studies have different results. Sometimes it is because of other factors (study done on healthy people in one case, on overweight people in the other case). One study may have measured the bacteria you are high in, the other did not. Similarly, one study may have measured the bacteria you are low in, the other did not. There is a forest of qualifications that are nearly impossibly complex to address, and if you try, it will often lack an objective decision that can be demonstrated ("I think...."). Where there are 'conflicts', my usual advice is to just omit it entirely from consideration. If you are taking it, keep taking it. It not, don't.


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